Evidence map›Paper›PMID 22779500›Full record

ArticleThe Journal of the Acoustical Society of America2012

Passive imaging with pulsed ultrasound insonations.

Kevin J Haworth, T Douglas Mast, Kirthi Radhakrishnan, Mark T Burgess, Jonathan A Kopechek, Shao-Ling Huang, David D McPherson, Christy K Holland

Abstract read
In one paragraph

Article in The Journal of the Acoustical Society of America, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 58 papers.

0numbers the graph read from it
0cells of the map it votes in
58citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

58 citing papers in PubMed.

  1. Article
  2. Article
  3. Overview of Therapeutic Ultrasound Applications and Safety Considerations: 2024 Update.Journal of ultrasound in medicine : official journal of the American Institute of Ultrasound in Medicine · 2025
    Review
  4. Article
  5. Article
  6. Article
  7. Article
  8. Passive Cavitation Imaging Artifact Reduction Using Data-Adaptive Spatial Filtering.IEEE transactions on ultrasonics, ferroelectrics, and frequency control · 2023
    Article
  9. Article
  10. Article
  11. Article
  12. Article
  13. Multifocused Ultrasound Therapy for Controlled Microvascular Permeabilization and Improved Drug Delivery.IEEE transactions on ultrasonics, ferroelectrics, and frequency control · 2021
    Article
  14. Real-Time Passive Acoustic Mapping Using Sparse Matrix Multiplication.IEEE transactions on ultrasonics, ferroelectrics, and frequency control · 2021
    Article
  15. Article
  16. Article
  17. Article
  18. Review
  19. Article
  20. Characterization of cavitation-radiated acoustic power using diffraction correction.The Journal of the Acoustical Society of America · 2018
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Kevin J HaworthDepartment of Internal Medicine, Division of Cardiovascular Diseases, University of Cincinnati, Cincinnati, Ohio, USA. kevin.haworth@uc.edu
T Douglas Mast
Kirthi Radhakrishnan
Mark T Burgess
Jonathan A Kopechek
Shao-Ling Huang
David D McPherson
Christy K Holland

Funding

U OF TEXAS HLTH SCI CTR HOUSTON CENTER FOR CLINICAL AND TRANSLATIONAL SCIENCESUL1RR024148 · NCRR · UNIVERSITY OF TEXAS HLTH SCI CTR HOUSTON · PI MCPHERSON, DAVID D · 2006 to 2010
$27.9M
Echogenic Targeted Liposomes:Transfection/Drug DeliveryR01HL074002 · NHLBI · UNIVERSITY OF TEXAS HLTH SCI CTR HOUSTON · PI MCPHERSON, DAVID D · 2004 to 2013
$5.3M
Real-time prediction of thermal ablation-induced cell death by echo decorrelationR01CA158439 · NCI · UNIVERSITY OF CINCINNATI · PI MAST, T DOUGLAS · 2012 to 2022
$3.4M
TARGETED LIPOSOMES FOR ACOUSTIC CARDIOVASCULAR IMAGINGR01HL059586 · NHLBI · UNIVERSITY OF TEXAS HLTH SCI CTR HOUSTON · PI MCPHERSON, DAVID D · 1998 to 2012
$3.2M
Passive Cavitation Imaging for Guidance and Control of Ultrasound AblationR21EB008483 · NIBIB · UNIVERSITY OF CINCINNATI · PI MAST, T DOUGLAS · 2009 to 2010
$387k
Passive Cavitation Image-Guided Ultrasound-Mediated Drug Delivery for Atheroma ThF32HL104916 · NHLBI · UNIVERSITY OF CINCINNATI · PI HAWORTH, KEVIN JOSEPH · 2010 to 2011
$103k
NCI NIH HHS R01 CA158439NCRR NIH HHS UL1 RR024148NHLBI NIH HHS F32 HL104916NHLBI NIH HHS F32HL104916NHLBI NIH HHS R01 HL059586NHLBI NIH HHS R01HL059586NHLBI NIH HHS R01 HL074002NHLBI NIH HHS R01HL074002NIBIB NIH HHS R21 EB008483NIBIB NIH HHS R21EB008483
6 · The paper itself

Abstract

Previously, passive cavitation imaging has been described in the context of continuous-wave high-intensity focused ultrasound thermal ablation. However, the technique has potential use as a feedback mechanism for pulsed-wave therapies, such as ultrasound-mediated drug delivery. In this paper, results of experiments and simulations are reported to demonstrate the feasibility of passive cavitation imaging using pulsed ultrasound insonations and how the images depend on pulsed ultrasound parameters. The passive cavitation images were formed from channel data that was beamformed in the frequency domain. Experiments were performed in an invitro flow phantom with an experimental echo contrast agent, echogenic liposomes, as cavitation nuclei. It was found that the pulse duration and envelope have minimal impact on the image resolution achieved. The passive cavitation image amplitude scales linearly with the cavitation emission energy. Cavitation images for both stable and inertial cavitation can be obtained from the same received data set.

Indexed as

AnimalsLiverMalePhantoms, ImagingRabbitsScattering, RadiationSound SpectrographyTransducers, PressureUltrasonics

Identifiers

PMID22779500
PMCPMC3407164

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.