ArticleEvidence-based complementary and alternative medicine : eCAM2012
Evaluation of the effects of acupuncture on blood flow in humans with ultrasound color Doppler imaging.
Article in Evidence-based complementary and alternative medicine : eCAM, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers, 2 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
24 citing papers in PubMed, 2 syntheses or guidelines pooled it, 51 citations in OpenAlex.
- Efficacy and safety of acupuncture in the treatment of chemotherapy-induced peripheral neuropathy in breast cancer patients: a systematic review and meta-analysis.Frontiers in neurology · 2025Pooled it
- The use of acupuncture in patients with Raynaud's syndrome: a systematic review and meta-analysis of randomized controlled trials.Acupuncture in medicine : journal of the British Medical Acupuncture Society · 2023Pooled it
- Randomized controlled trial of electro-stimulation therapies to modulate retinal blood flow and visual function in retinitis pigmentosa.Acta ophthalmologica · 2018Trial
- Hemodynamic changes caused by acupuncture in healthy volunteers: a prospective, single-arm exploratory clinical study.BMC complementary and alternative medicine · 2017Trial
- Acupuncture combined with methylcobalamin for the treatment of chemotherapy-induced peripheral neuropathy in patients with multiple myeloma.BMC cancer · 2017Trial
- A Randomized Sham-Controlled Mixed Methods Pilot Study of the Feasibility of Acupuncture for Chemotherapy-Induced Neuropathy: Lessons Learned From Patient Experiences in Integrative Cancer Care.Integrative cancer therapiesTrial
- Hemodynamic Changes Following Acupuncture and Moxibustion in Patients with Subjective Tinnitus: An Acceleration Photoplethysmography and Pulsed-Wave Doppler Ultrasound Study.Audiology research · 2026Article
- Electroacupuncture-augmented breaststroke vs. breaststroke alone for mild AIS: superior correction in a retrospective cohort.Frontiers in pediatrics · 2026Article
- Perspective on acupuncture treatment for diabetic peripheral neuropathy: A perspective.Medicine · 2025Review
- Acupuncture in Dentistry: A Comprehensive Review of Its Applications, Mechanisms, and Clinical Efficacy.Cureus · 2025Review
- The vasodilatory effect of acupuncture and medicine-cake-separated moxibustion on a 28-year course of Takayasu arteritis: a case report.Frontiers in cardiovascular medicine · 2025Article
- Acupuncture as Adjuvant Therapy for Glaucoma: Protocol for a Randomized Controlled Trial.JMIR research protocols · 2024Article
- The State of 21st Century Acupuncture in the United States.Journal of pain research · 2024Article
- Effects of Electrical Stimulation of the Cell: Wound Healing, Cell Proliferation, Apoptosis, and Signal Transduction.Medical sciences (Basel, Switzerland) · 2023Article
- Acupuncture in Multidisciplinary Treatment for Post-COVID-19 Syndrome.Medical acupuncture · 2022Article
- Laser acupuncture for claudication symptoms in peripheral artery disease - Does it work? A randomized trial.Hong Kong physiotherapy journal : official publication of the Hong Kong Physiotherapy Association Limited = Wu li chih liao · 2022Article
- Acupuncture Differentially Affects the High-Frequency Spectral Energy in Radial Pulse Positions Depending on Type of Lower Back Pain.Evidence-based complementary and alternative medicine : eCAM · 2019Article
- Delayed recovery of pediatric sudden sensorineural hearing loss treated with acupuncture: A case report.Medicine · 2018Article
- The short-term effect of acupuncture on different ocular blood flow parameters in patients with primary open-angle glaucoma: a randomized, clinical study.Clinical ophthalmology (Auckland, N.Z.) · 2018Article
- Comment on "The short-term effect of acupuncture on different ocular blood flow parameters in patients with primary open-angle glaucoma: a randomized, clinical study".Clinical ophthalmology (Auckland, N.Z.) · 2018Article
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Authors and funding
7 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Color Doppler imaging (CDI) can be used to noninvasively create images of human blood vessels and quantitatively evaluate blood flow in real-time. The purpose of this study was to assess the effects of acupuncture on the blood flow of the peripheral, mesenteric, and retrobulbar arteries by CDI. Statistical significance was defined as P values less than 0.05. Blood flow in the radial and brachial arteries was significantly lower during needle stimulation on LR3 than before in healthy volunteers, but was significantly higher after needle stimulation than before. LR3 stimulation also resulted in a significant decrease in the vascular resistance of the short posterior ciliary artery and no significant change of blood flow through the superior mesenteric artery (SMA) during acupuncture. In contrast, ST36 stimulation resulted in a significant increase in blood flow through the SMA and no significant change in the vascular resistance of the retrobulbar arteries. Additionally, acupuncture at previously determined acupoints in patients with open-angle glaucoma led to a significant reduction in the vascular resistance of the central retinal artery and short posterior ciliary artery. Our results suggest that acupuncture can affect blood flow of the peripheral, mesenteric, and retrobulbar arteries, and CDI can be useful to evaluate hemodynamic changes by acupuncture.
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.