Evidence map›Paper›PMID 22778606›Full record

ArticleSensors (Basel, Switzerland)2012

Time-domain fluorescence lifetime imaging techniques suitable for solid-state imaging sensor arrays.

David Day-Uei Li, Simon Ameer-Beg, Jochen Arlt, David Tyndall, Richard Walker, Daniel R Matthews, Viput Visitkul, Justin Richardson, Robert K Henderson

Abstract read
In one paragraph

Article in Sensors (Basel, Switzerland), 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed.

  1. Article
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  4. Article
  5. Fast Gating for Raman Spectroscopy.Sensors (Basel, Switzerland) · 2021
    Review
  6. Article
  7. Article
  8. Review
  9. Article
  10. Article
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  12. Article
  13. Frequency MultiplexedNature photonics · 2013
    Article
  14. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

David Day-Uei LiDepartment of Engineering and Design, School of Engineering and Informatics, University of Sussex, Brighton BN1 9QT, UK. david.li@sussex.ac.uk
Simon Ameer-Beg
Jochen Arlt
David Tyndall
Richard Walker
Daniel R Matthews
Viput Visitkul
Justin Richardson
Robert K Henderson

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

We have successfully demonstrated video-rate CMOS single-photon avalanche diode (SPAD)-based cameras for fluorescence lifetime imaging microscopy (FLIM) by applying innovative FLIM algorithms. We also review and compare several time-domain techniques and solid-state FLIM systems, and adapt the proposed algorithms for massive CMOS SPAD-based arrays and hardware implementations. The theoretical error equations are derived and their performances are demonstrated on the data obtained from 0.13 μm CMOS SPAD arrays and the multiple-decay data obtained from scanning PMT systems. In vivo two photon fluorescence lifetime imaging data of FITC-albumin labeled vasculature of a P22 rat carcinosarcoma (BD9 rat window chamber) are used to test how different algorithms perform on bi-decay data. The proposed techniques are capable of producing lifetime images with enough contrast.

Indexed as

CMOSFLIMfluorescence lifetime imaging microscopylifetime based sensingmulti-decaysingle-decaysingle-photon avalanche diodetime-domain FLIM

Identifiers

PMID22778606
PMCPMC3386705

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.