Evidence map›Paper›PMID 22778335›Full record

ArticleHealth affairs (Project Hope)2012

In a study of a population cohort in South Africa, HIV patients on antiretrovirals had nearly full recovery of employment.

Jacob Bor, Frank Tanser, Marie-Louise Newell, Till Bärnighausen

Open access · greenAbstract read
In one paragraph

Article in Health affairs (Project Hope), 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 69 papers, 5 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
69citing papers in PubMed, 5 pooled it
6.1field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

69 citing papers in PubMed, 5 syntheses or guidelines pooled it, 116 citations in OpenAlex.

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  3. Interventions for improving employment outcomes for workers with HIV.The Cochrane database of systematic reviews · 2015
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9 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 4 institutions in 4 countries.

Jacob BorHarvard School of Public Health, Boston, MA, USA. jbor@hsph.harvard.edu
Frank Tanser
Marie-Louise Newell
Till Bärnighausen
Africa Health Research Institute · ZAHarvard Global Health Institute · USInstitute of Child Health · INNational Bureau of Economic Research · US

Funding

Impact of Antiretroviral Therapy on HIV Epidemic DynamicsR01MH083539 · NIMH · BROWN UNIVERSITY · PI LURIE, MARK NATHAN · 2009 to 2012
$2.2M
Understanding causal pathways of HIV acquisition and transmission: a multi-level,R01HD058482 · NICHD · UNIVERSITY OF KWAZULU-NATAL · PI BARNIGHAUSEN, TILL, TANSER, FRANK COURTENEY · 2008 to 2012
$1.2M
NICHD NIH HHS R01 HD058482NICHD NIH HHS R01 HD058482-01NIMH NIH HHS 1R01MH083539-01NIMH NIH HHS R01 MH083539PEPFARWellcome Trust 097410
6 · The paper itself

Abstract

Antiretroviral therapy for HIV may have important economic benefits for patients and their households. We quantified the impact of HIV treatment on employment status among HIV patients in rural South Africa who were enrolled in a public-sector HIV treatment program supported by the President's Emergency Plan for AIDS Relief. We linked clinical data from more than 2,000 patients in the treatment program with ten years of longitudinal socioeconomic data from a complete community-based population cohort of more than 30,000 adults residing in the clinical catchment area. We estimated the employment effects of HIV treatment in fixed-effects regressions. Four years after the initiation of antiretroviral therapy, employment among HIV patients had recovered to about 90 percent of baseline rates observed in the same patients three to five years before they started treatment. Many patients initiated treatment early enough that they were able to avoid any loss of employment due to HIV. These results represent the first estimates of employment recovery among HIV patients in a general population, relative to the employment levels that these patients had prior to job-threatening HIV illness and the decision to seek care. There are large economic benefits to HIV treatment. For some patients, further gains could be obtained from initiating antiretroviral therapy earlier, prior to HIV-related job loss.

Indexed as

EmploymentActivities of Daily LivingAdolescentAdultAnti-HIV AgentsCD4 Lymphocyte CountFemaleHIV InfectionsHumansInternational CooperationLongitudinal StudiesMaleMiddle AgedSick LeaveSocioeconomic FactorsSouth AfricaAnti-HIV Agents

Identifiers

PMID22778335
PMCPMC3819460
OpenAlexW2110579674

What OpenQuestion holds

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LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.