ArticlePediatrics2012
Choriophobia: a 1-act play.
Article in Pediatrics, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT03168178 (A Randomized Trial in Intrapartum Fever Of No Antibiotics for Low-risk Women), which is not on this map. Cited by 11 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
A Randomized Trial in Intrapartum Fever Of No Antibiotics for Low-risk Women (RATIONAL)
Who cites it
11 citing papers in PubMed, 30 citations in OpenAlex.
- Article
- Early-Onset Sepsis Risk Calculator Integration Into an Electronic Health Record in the Nursery.Pediatrics · 2019Article
- Determinants of Initial Antibiotic Duration in Very Low Birth Weight Neonates.Infectious diseases and therapy · 2019Article
- Induction of labor and early-onset Sepsis guidelines: impact on NICU admissions in Erie County, NY.Maternal health, neonatology and perinatology · 2019Article
- Neonatal Antibiotic Use: How Much Is Too Much?Pediatrics · 2018Article
- Anti-microbial stewardship: antibiotic use in well-appearing term neonates born to mothers with chorioamnionitis.Journal of perinatology : official journal of the California Perinatal Association · 2017Article
- Clinical chorioamnionitis at term I: microbiology of the amniotic cavity using cultivation and molecular techniques.Journal of perinatal medicine · 2015Article
- Chorioamnionitis: epidemiology of newborn management and outcome United States 2008.Journal of perinatology : official journal of the California Perinatal Association · 2014Article
- Variability of physicians' thresholds for neuroimaging in children with recurrent headache.BMC pediatrics · 2014Article
- Article
- Resource Utilization and Costs Associated with Approaches to Identify Infants with Early-Onset Sepsis.MDM policy & practiceArticle
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors at 1 institution in 1 country.
Funding
Abstract
The management of a newborn born to a mother with chorioamnionitis is controversial. By using data collected on neonates born in the era of routine maternal screening for Group B Streptococcus, we calculate that the risk of early-onset sepsis in a hypothetical infant born at term to a mother with chorioamnionitis, who has a normal physical examination at birth, is likely substantially <1% if the mother's screen for Group B Streptococcus was negative. This low rate of sepsis calls into question current guidelines recommending treatment of all such newborns with intravenous antibiotics for 48 hours pending the results of a blood culture. Current guidelines for the management of infants born to mothers with chorioamnionitis also raise an important ethical issue; the recommendation to treat these infants with intravenous antibiotics is, in essence, a de facto determination of what constitutes unacceptable risk to the newborn. We argue that this determination is ultimately value-based and therefore requires broader deliberation than that which frequently occurs among medical experts who develop medical guidelines.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.