ArticleSmall (Weinheim an der Bergstrasse, Germany)2012
Small molecule-gold nanorod conjugates selectively target and induce macrophage cytotoxicity towards breast cancer cells.
Article in Small (Weinheim an der Bergstrasse, Germany), 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 29 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
29 citing papers in PubMed.
- The evolution of immune profiling: will there be a role for nanoparticles?Nanoscale horizons · 2024Review
- Tumor-associated macrophages in nanomaterial-based anti-tumor therapy: as target spots or delivery platforms.Frontiers in bioengineering and biotechnology · 2023Review
- Treasure on the Earth-Gold Nanoparticles and Their Biomedical Applications.Materials (Basel, Switzerland) · 2022Review
- Nanomedicine as a Promising Tool to Overcome Immune Escape in Breast Cancer.Pharmaceutics · 2022Review
- Article
- Design and Encapsulation of Immunomodulators onto Gold Nanoparticles in Cancer Immunotherapy.International journal of molecular sciences · 2021Review
- Tailoring Materials for Modulation of Macrophage Fate.Advanced materials (Deerfield Beach, Fla.) · 2021Review
- Article
- Gold nanoparticles in chemo-, immuno-, and combined therapy: review [Invited].Biomedical optics express · 2019Article
- Green synthesis of gold nanoparticles usingInternational journal of nanomedicine · 2019Article
- Harnessing Macrophages for Controlled-Release Drug Delivery: Lessons From Microbes.Frontiers in pharmacology · 2019Review
- Photochemical internalization enhanced macrophage delivered chemotherapy.Photodiagnosis and photodynamic therapy · 2018Article
- Uptake, distribution, clearance, and toxicity of iron oxide nanoparticles with different sizes and coatings.Scientific reports · 2018Article
- Cellular uptake of nanoparticles: journey inside the cell.Chemical Society reviews · 2017Review
- Immunological properties of gold nanoparticles.Chemical science · 2017Article
- Engineering nanolayered particles for modular drug delivery.Journal of controlled release : official journal of the Controlled Release Society · 2016Review
- Preparation and Photoacoustic Analysis of Cellular Vehicles Containing Gold Nanorods.Journal of visualized experiments : JoVE · 2016Article
- Uniform brain tumor distribution and tumor associated macrophage targeting of systemically administered dendrimers.Biomaterials · 2015Article
- Nanoscale materials for hyperthermal theranostics.Nanoscale · 2015Review
- P-glycoprotein-dependent trafficking of nanoparticle-drug conjugates.Small (Weinheim an der Bergstrasse, Germany) · 2014Article
Corrections and comments
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Authors and funding
6 authors.
Funding
Abstract
Gold nanoparticles are known to activate anti-tumor potential in macrophage immune cells; however, the subsequent effects of these cells on others nearby are poorly understood. A novel gold-nanoparticle conjugate that selectively targets and induces cytotoxic activity of tumor-associated macrophages towards breast cancer cells in co-culture is synthesized. These constructs are promising new tools for studying fundamental biological interactions with nanoscale materials and candidates for emerging macrophage-mediated delivery applications.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.