ArticleNeuroreport2012
Intracortical convergence of layer 6 neurons.
Article in Neuroreport, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.
What it found
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
20 citing papers in PubMed.
- Layer 5 and 6b extratelencephalic neurons encode distinct sound features in auditory cortex.bioRxiv : the preprint server for biology · 2026Article
- Neuroanatomical Alterations in the CNTNAP2 Mouse Model of Autism Spectrum Disorder.Brain sciences · 2023Article
- Information flow in the rat thalamo-cortical system: spontaneous vs. stimulus-evoked activities.Scientific reports · 2021Article
- Lemniscal Corticothalamic Feedback in Auditory Scene Analysis.Frontiers in neuroscience · 2021Review
- Crossed Connections From Insular Cortex to the Contralateral Thalamus.Frontiers in neural circuits · 2021Article
- Development, organization and plasticity of auditory circuits: Lessons from a cherished colleague.The European journal of neuroscience · 2019Review
- Activation of Corticothalamic Layer 6 Cells Decreases Angular Tuning in Mouse Barrel Cortex.Frontiers in neural circuits · 2019Article
- Functional Topography and Development of Inhibitory Reticulothalamic Barreloid Projections.Frontiers in neuroanatomy · 2018Article
- A Corticothalamic Circuit for Dynamic Switching between Feature Detection and Discrimination.Neuron · 2017Article
- A Neurophysiological Perspective on a Preventive Treatment against Schizophrenia Using Transcranial Electric Stimulation of the Corticothalamic Pathway.Brain sciences · 2017Review
- Thalamus plays a central role in ongoing cortical functioning.Nature neuroscience · 2016Review
- Spatial organization of excitatory synaptic inputs to layer 4 neurons in mouse primary auditory cortex.Frontiers in neural circuits · 2015Article
- Two types of auditory glutamatergic synapses and their implications for repairing damaged central auditory pathways.Neural regeneration research · 2014Article
- Cortical control of adaptation and sensory relay mode in the thalamus.Proceedings of the National Academy of Sciences of the United States of America · 2014Article
- Simultaneous visualization of extrinsic and intrinsic axon collaterals in Golgi-like detail for mouse corticothalamic and corticocortical cells: a double viral infection method.Frontiers in neural circuits · 2014Article
- Laser-scanning photostimulation of optogenetically targeted forebrain circuits.Journal of visualized experiments : JoVE · 2013Article
- Functional convergence of thalamic and intrinsic projections to cortical layers 4 and 6.Neurophysiology · 2013Article
- Thalamic and cortical pathways supporting auditory processing.Brain and language · 2013Review
- Reciprocal Homosynaptic and heterosynaptic long-term plasticity of corticogeniculate projection neurons in layer VI of the mouse visual cortex.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2013Article
- Activation requirements for metabotropic glutamate receptors.Neuroscience letters · 2013Article
Corrections and comments
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Authors and funding
3 authors.
Funding
Abstract
Axonal branches from a subset of neurons in cerebral cortical layer 6 innervate both cortical layer 4 and the thalamus. As such, these neurons are poised to modulate thalamocortical transmission at multiple forebrain sites. Here, we examined the functional organization of the layer 6 intracortical projections in auditory, somatosensory, and visual cortical areas using an optogenetic approach to specifically target these neurons. We characterized the anatomical and physiological organization of these projections using laser-scanning photostimulation to functionally map the elicited postsynaptic responses in layer 4. We found that these responses originated from regions over 1 mm in width, eliciting short-term facilitating responses. These results indicate that intracortical modulation of layer 4 occurs through widespread layer 6 projections in each sensory cortical area.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.