Evidence map›Paper›PMID 22775287›Full record

ArticleJournal of public health dentistry2013

Periodontitis associated with chronic kidney disease among Mexican Americans.

Effie Ioannidou, Yoshio Hall, Helen Swede, Jonathan Himmelfarb

Registry-linked trialOpen access · greenAbstract read
In one paragraph

Article in Journal of public health dentistry, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT01094639 (Periodontal Infection and Systemic Inflammation in Renal Patients), which is not on this map. Cited by 20 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed, 1 pooled it
1.0field-weighted citation impact, top 27% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT01094639 nacompletednot on this map

Periodontal Infection and Systemic Inflammation in Renal Patients

TypeinterventionalSponsorUConn HealthRan2009 to 2015Enrolled52ConditionsPeriodontitis, Chronic Kidney DiseaseArmsScaling root planing, Supragingival Prophylaxis
3 · Its place in the literature

Who cites it

20 citing papers in PubMed, 1 synthesis or guideline pooled it, 37 citations in OpenAlex.

  1. [Oral health status of patients undergoing hemodialysis: a Meta-analysis].Hua xi kou qiang yi xue za zhi = Huaxi kouqiang yixue zazhi = West China journal of stomatology · 2017
    Pooled it
  2. Review
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  8. Chronic Kidney Disease and Periodontitis Interplay-A Narrative Review.International journal of environmental research and public health · 2023
    Review
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  11. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

Effie IoannidouDivision of Periodontology, Department of Oral Health and Diagnostic Sciences, University of Connecticut Health Center, Farmington, CT 06030-1710, USA. ioannidou@uchc.edu
Yoshio Hall
Helen Swede
Jonathan Himmelfarb
UConn Health · USUniversity of Washington · US

Funding

ZONISAMIDE VERSUS PLACEBOM01RR006192 · NCRR · UNIVERSITY OF CONNECTICUT SCH OF MED/DNT · PI DRAZINIC, CAROLYN M · 1994 to 2008
$22.1M
Chronic Kidney Disease in Disadvantaged PopulationsK23DK087900 · NIDDK · UNIVERSITY OF WASHINGTON · PI HALL, YOSHIO N. · 2010 to 2014
$865k
Peridontal Infection and systemic inflammation in renal patientsK23DE018689 · NIDCR · UNIVERSITY OF CONNECTICUT SCH OF MED/DNT · PI IOANNIDOU, EFTHIMIA · 2009 to 2013
$699k
NCRR NIH HHS M01 RR006192NCRR NIH HHS M01RR06192NIDCR NIH HHS K23 DE018689NIDCR NIH HHS K23DE018689NIDDK NIH HHS K23 DK087900
6 · The paper itself

Abstract

objectiveIn comparison to non-Hispanic whites, a number of health-care disparities, including poor oral health, have been identified among Hispanics in general and Mexican Americans in particular. We hypothesized that Mexican Americans with chronic kidney disease (CKD) would have higher prevalence of chronic periodontitis compared with Mexican Americans with normal kidney function, and that the level of kidney function would be inversely related to the prevalence of periodontal disease.

methodsWe examined this hypothesis using the National Health and Nutrition Examination Survey 1988-1994 (NHANES III) data set. We followed the American Academy of Periodontology/Center for Disease Control and Prevention case definition for periodontitis. Glomerular filtration rate was estimated using the CKD-Epidemiology equation for Hispanic populations. The classification to CKD stages was based on the National Kidney Foundation Kidney Disease Outcomes Quality Initiative.

resultsPeriodontitis prevalence increased across the kidney function groups showing a statistically significant dose-response association (P<0.001). Mexican Americans with reduced kidney function were twofold more likely to have periodontitis compared with Mexican Americans with normal kidney function after adjusting for potential confounders such as smoking, diabetes, and socioeconomic status. Multivariate adjusted odds ratio for periodontitis significantly increased with 1, 5, and 10 mL/minute estimated glomerular filtration rate reduction from the mean.

conclusionThis is the first report, to the best our knowledge, that showed an increase of periodontitis prevalence with decreased kidney function in this population.

Indexed as

Mexican AmericansAdultFemaleHumansKidney Failure, ChronicMaleMiddle AgedNutrition SurveysPeriodontitisUnited States

Identifiers

PMID22775287
PMCPMC3470761
OpenAlexW1846996209

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.