Evidence map›Paper›PMID 22773426›Full record

ReviewCirculation research2012

Molecular imaging of atherosclerosis for improving diagnostic and therapeutic development.

Thibaut Quillard, Peter Libby

Abstract readReview
In one paragraph

Review in Circulation research, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 71 papers.

0numbers the graph read from it
0cells of the map it votes in
71citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

71 citing papers in PubMed.

  1. Review
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  5. Review
  6. Article
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  11. Article
  12. Review
  13. Imaging inflammation in atherosclerotic plaques, targeting SSTJournal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2021
    Article
  14. Article
  15. Article
  16. Article
  17. Nanoparticles target intimal macrophages in atherosclerotic lesions.Nanomedicine : nanotechnology, biology, and medicine · 2021
    Article
  18. Review
  19. Review
  20. Review

11 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Thibaut QuillardDivision of Cardiovascular Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, MA 02115, USA.
Peter Libby

Funding

Translational Program of Excellence in NanotechnologyU01HL080731 · NHLBI · MASSACHUSETTS GENERAL HOSPITAL · PI WEISSLEDER, MD, PHD, RALPH · 2005 to 2009
$14.9M
Molecular Determinants of Arterial Remodeling in AtherogenesisR01HL080472 · NHLBI · BRIGHAM AND WOMEN'S HOSPITAL · PI LIBBY, PETER · 2005 to 2018
$5.0M
NHLBI NIH HHS R01 HL080472NHLBI NIH HHS R01-HL080472NHLBI NIH HHS U01 HL080731
6 · The paper itself

Abstract

Despite recent progress, cardiovascular and allied metabolic disorders remain a worldwide health challenge. We must identify new targets for therapy, develop new agents for clinical use, and deploy them in a clinically effective and cost-effective manner. Molecular imaging of atherosclerotic lesions has become a major experimental tool in the last decade, notably by providing a direct gateway to the processes involved in atherogenesis and its complications. This review summarizes the current status of molecular imaging approaches that target the key processes implicated in plaque formation, development, and disruption and highlights how the refinement and application of such tools might aid the development and evaluation of novel therapeutics.

Indexed as

AnimalsAtherosclerosisHumansMolecular ImagingOxidative StressPlaque, Atherosclerotic

Identifiers

PMID22773426
PMCPMC3412367

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.