Evidence map›Paper›PMID 22773365›Full record

ReviewCurrent psychiatry reports2012

Mild cognitive impairment in older adults.

Yonas E Geda

Registry-linked trialAbstract readReview
In one paragraph

Review in Current psychiatry reports, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05974605 (Mindfulness and Attention Training Intervention to Lower Distractibility in Aging), which is not on this map. Cited by 51 papers, 6 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
51citing papers in PubMed, 6 pooled it
2.1field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT05974605 nacompletednot on this mapstarted 2022, after this paper: background citation

Mindfulness and Attention Training Intervention to Lower Distractibility in Aging

TypeinterventionalSponsorThe University of Texas at DallasRan2022 to 2024Enrolled16ConditionsHealthy AgingArmsMM+HighC
3 · Its place in the literature

Who cites it

51 citing papers in PubMed, 6 syntheses or guidelines pooled it, 110 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

1 author at 1 institution in 1 country.

Yonas E GedaDepartment of Psychiatry and Psychology, Mayo Clinic, Scottsdale, AZ, USA. geda.yonas@mayo.edu
Mayo Clinic · US

Funding

TRIAL OF VALPROATE TO ATTENUATE THE PROGRESSION OF ADU01AG010483 · NIA · UNIVERSITY OF ROCHESTER · PI AISEN, PAUL S. · 1991 to 2012
$116.2M
MAYO CLINIC CENTER FOR TRANSLATIONAL SCIENCE ACTIVITIESUL1RR024150 · NCRR · MAYO CLINIC ROCHESTER · PI RIZZA, ROBERT A. · 2006 to 2011
$66.4M
SUPPLEMENT TO ALZHEIMERS DISEASE PATIENT REGISTRYU01AG006786 · NIA · MAYO CLINIC ROCHESTER · PI GRAFF-RADFORD, JONATHAN, JACK, CLIFFORD R. · 1986 to 2023
$49.6M
THE PGRN/TDP-43 AXIS IN ALZHEIMER?S DISEASE AND NEURODEGENERATIONP50AG016574 · NIA · MAYO CLINIC ROCHESTER · PI BU, GUOJUN · 1999 to 2018
$36.9M
Psychiatric Characterization/Mild Cognitive ImpairmentK01MH068351 · NIMH · MAYO CLINIC ROCHESTER · PI GEDA, YONAS E · 2004 to 2008
$890k
NCRR NIH HHS RR024150NIA NIH HHS P50 AG016574NIA NIH HHS P50 AG16574NIA NIH HHS U01 AG006786NIA NIH HHS U01 AG010483NIA NIH HHS U01 AG06786NIMH NIH HHS K01 MH068351NIMH NIH HHS K01 MH68351
6 · The paper itself

Abstract

Mild cognitive impairment (MCI) is the intermediate stage between the cognitive changes of normal aging and dementia. MCI is important because it constitutes a high risk group for dementia. Ideally, prevention strategies should target individuals who are not even symptomatic. Indeed, the field is now moving towards identification of asymptomatic individuals who have underlying Alzheimer's disease (AD) pathology that can be detected using biomarkers and neuroimaging technologies. To this effect, the Alzheimer's Association and the National Institute on Aging have developed a new classification scheme that has categorized AD into a preclinical phase (research category), MCI due to AD, and dementia of Alzheimer's type. However, there are also ongoing research studies to understand high-risk groups for non-Alzheimer's dementia.

Indexed as

AgedAged, 80 and overAlzheimer DiseaseCognitive DysfunctionDisease ProgressionHumansIncidenceNeuroimagingPrevalencePsychiatric Status Rating ScalesPsychometricsSex DistributionUnited States

Identifiers

PMID22773365
PMCPMC3963488
OpenAlexW2040428649

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.