ArticleMolecular genetics and genomics : MGG2012
Natural epigenetic variation in the female great roundleaf bat (Hipposideros armiger) populations.
Article in Molecular genetics and genomics : MGG, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.
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Who cites it
20 citing papers in PubMed, 55 citations in OpenAlex.
- Epigenetics in forest trees- key driver to phenotypic plasticity and adaptation under stress.Functional & integrative genomics · 2025Review
- DNA methylation variation and growth in the clonalEpigenetics · 2024Article
- Full-Length Transcriptome of the Great Himalayan Leaf-Nosed Bats (International journal of molecular sciences · 2023Article
- Population Epigenetics: The Extent of DNA Methylation Variation in Wild Animal Populations.Epigenomes · 2022Review
- Population differences in Chinook salmon (Ecology and evolution · 2021Article
- Patterns of Epigenetic Diversity in Two Sympatric Fish Species: Genetic vs. Environmental Determinants.Genes · 2021Article
- Rearing environment affects the genetic architecture and plasticity of DNA methylation in Chinook salmon.Heredity · 2021Article
- Ultraviolet B Radiation Triggers DNA Methylation Change and Affects Foraging Behavior of the Clonal PlantFrontiers in plant science · 2021Article
- Heritable epigenetic diversity for conservation and utilization of epigenetic germplasm resources of clonal East African Highland banana (EAHB) accessions.TAG. Theoretical and applied genetics. Theoretische und angewandte Genetik · 2020Article
- Characterization of Genetic and Epigenetic Variation in Sperm and Red Blood Cells from Adult Hatchery and Natural-Origin Steelhead,G3 (Bethesda, Md.) · 2018Article
- Epigenetic and genetic variation among three separate introductions of the house sparrow (Royal Society open science · 2018Article
- Epigenetic Variance, Performing Cooperative Structure with Genetics, Is Associated with Leaf Shape Traits in Widely Distributed Populations of Ornamental TreeFrontiers in plant science · 2018Article
- Small ocean temperature increases elicit stage-dependent changes in DNA methylation and gene expression in a fish, the European sea bass.Scientific reports · 2017Article
- Epigenetic variation between urban and rural populations of Darwin's finches.BMC evolutionary biology · 2017Article
- Epigenetic response to environmental change: DNA methylation varies with invasion status.Environmental epigenetics · 2016Article
- BsRADseq: screening DNA methylation in natural populations of non-model species.Molecular ecology · 2016Article
- The complex pattern of epigenomic variation between natural yeast strains at single-nucleosome resolution.Epigenetics & chromatin · 2015Article
- Fine-scale population epigenetic structure in relation to gastrointestinal parasite load in red grouse (Lagopus lagopus scotica).Molecular ecology · 2014Article
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Corrections and comments
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Authors and funding
6 authors at 2 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Epigenetic modifications are considered to have an important role in evolution. DNA methylation is one of the best studied epigenetic mechanisms and methylation variability is crucial for promoting phenotypic diversification of organisms in response to environmental variation. A critical first step in the assessment of the potential role of epigenetic variation in evolution is the identification of DNA methylation polymorphisms and their relationship with genetic variations in natural populations. However, empirical data is scant in animals, and particularly so in wild mammals. Bats are considered as bioindicators because of their sensitivity to environmental perturbations and they may present an opportunity to explore epigenetic variance in wild mammalian populations. Our study is the first to explore these questions in the female great roundleaf bat (Hipposideros armiger) populations using the methylation-sensitive amplified polymorphism (MSAP) technique. We obtained 868 MSAP sites using 18 primer combinations and found (1) a low genomic methylation level (21.3 % on average), but extensive DNA methylation polymorphism (90.2 %) at 5'-CCGG-3' sites; (2) epigenetic variation that is structured into distinct between- (29.8 %) and within- (71.2 %) population components, as does genetic variation; and (3) a significant correlation between epigenetic and genetic variations (P < 0.05). These results may also apply to other wild mammalian populations. The possible causes for the correlation between epigenetic and genetic variations are discussed.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.