ArticleClinical research in cardiology : official journal of the German Cardiac Society2012
Transcatheter aortic valve implantation in patients with and without concomitant coronary artery disease: comparison of characteristics and early outcome in the German multicenter TAVI registry.
Article in Clinical research in cardiology : official journal of the German Cardiac Society, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 40 papers.
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Who cites it
40 citing papers in PubMed, 98 citations in OpenAlex.
- Outcomes of complex, high-risk percutaneous coronary intervention in patients with severe aortic stenosis: the ASCoP registry.EuroIntervention : journal of EuroPCR in collaboration with the Working Group on Interventional Cardiology of the European Society of Cardiology · 2025Trial
- Impact of left ventricular conduction defect with or without need for permanent right ventricular pacing on functional and clinical recovery after TAVR.Clinical research in cardiology : official journal of the German Cardiac Society · 2015Trial
- Feasibility of sheathless transfemoral aortic valve implantation in patients with small access vessel diameters.Clinical research in cardiology : official journal of the German Cardiac Society · 2014Trial
- Trial
- TAVI plus PCI versus SAVR plus CABG: Long-term outcome of a multicentre-registry.Clinical research in cardiology : official journal of the German Cardiac Society · 2026Article
- Value of Coronary CT Angiography in Ruling Out Coronary Artery Disease in Elderly Patients Candidates to TAVI.Journal of personalized medicine · 2026Article
- How to Individualize Coronary Assessment and Revascularization in Severe AS Patients Undergoing TAVI in the Era of Lifetime Management?Journal of clinical medicine · 2026Review
- Coronary artery disease in patients undergoing transcatheter aortic valve replacement: Current evidence and future directions.American heart journal plus : cardiology research and practice · 2026Review
- Impact of Prior Q-Wave Myocardial Infarction in Transcatheter Aortic Valve Replacement Patients With Reduced Ejection Fraction.Structural heart : the journal of the Heart Team · 2025Article
- Co-Occurrence of Aortic Stenosis and Coronary Artery Disease: Facing Challenges Before, During, and After Transcatheter Aortic Valve Replacement.Journal of clinical medicine · 2025Review
- Prognostic implications of pre-transcatheter aortic valve replacement computed tomography-derived coronary plaque characteristics and stenosis severity.European radiology · 2024Article
- Advanced CT measures of coronary artery disease with intermediate stenosis in patients with severe aortic valve stenosis.European radiology · 2024Article
- The impact of concomitant chronic total occlusion on clinical outcomes in patients undergoing transcatheter aortic valve replacement: a large single-center analysis.Frontiers in cardiovascular medicine · 2024Article
- Impact of previous coronary artery revascularization on outcomes in patients undergoing transcatheter aortic valve implantation.Postepy w kardiologii interwencyjnej = Advances in interventional cardiology · 2023Article
- Management of coronary artery disease in patients undergoing transcatheter aortic valve implantation. A clinical consensus statement from the European Association of Percutaneous Cardiovascular Interventions in collaboration with the ESC Working Group on Cardiovascular Surgery.EuroIntervention : journal of EuroPCR in collaboration with the Working Group on Interventional Cardiology of the European Society of Cardiology · 2023Article
- Acute Kidney Injury Following Transcatheter Aortic Valve Implantation: Association with Contrast Media Dosage and Contrast Media Based Risk Predication Models.Journal of clinical medicine · 2022Article
- Coronary Artery Disease in Patients Undergoing Transvalvular Aortic Valve Implantation.Interventional cardiology (London, England) · 2022Review
- Impact of extent of coronary artery disease and percutaneous revascularization assessed by the SYNTAX score on outcomes following transcatheter aortic valve replacement.BMC cardiovascular disorders · 2021Observational
- Pathophysiology, Diagnosis, and Treatment of Patients with Concomitant Severe Aortic Stenosis and Coronary Artery Disease: A Closer Look to the Unresolved Perplexity.Journal of clinical medicine · 2021Review
- Aortic Valve Disease and Associated Complex CAD: The Interventional Approach.Journal of clinical medicine · 2021Review
Corrections and comments
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Authors and funding
11 authors at 9 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectiveTo examine the prevalence and impact of concomitant coronary artery disease (CAD) on short-term outcome after transcatheter aortic valve implantation (TAVI).
backgroundThe prevalence of CAD in patients undergoing surgical aortic valve replacement is estimated at 30-50 % and its presence increases procedural risk. The prevalence and impact of CAD on outcome after TAVI are not well defined.
methodsWe analyzed 1,382 patients enrolled in the German TAVI registry; the majority (81 %) received the Medtronic CoreValve. The presence of coronary lesions with ≥50 % stenosis on pre-TAVI angiography defined the existence of concomitant CAD.
results859 patients (62.2 %) had concomitant CAD, of which 534 (62.3 %) had multi-vessel and 83 (9.7 %) left main disease. Patients with CAD were younger (81.5 ± 6.1 vs. 82.1 ± 6.3 years, p < 0.05), more commonly males (49.4 vs. 30.0 %, p < 0.0001) and diabetics (36.9 vs. 31.2 %, p < 0.05), and had a worse Canadian Cardiovascular Society angina class at baseline compared to patients with no CAD. During TAVI patients with CAD more often required additional coronary intervention and had longer procedures, but procedural success rates were similar (97.1 vs. 97.7 %). Crude in-hospital mortality was higher in patients with CAD (10.0 vs. 5.5 %, OR 1.90, 95 % CI 1.23-2.93), but this was not significant after adjustment for confounders (adjusted OR 1.41, 95 % CI 0.85-2.33). Both groups had significant improvement in 30-day symptoms and quality of life.
conclusionThe prevalence of CAD in contemporary TAVI patients is high. Its presence characterizes a high-risk population and is associated with increased crude short-term mortality, largely explained by co-morbidities, but does not limit functional improvement after TAVI.
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