ArticleNature medicine2012
After Xigris, researchers look to new targets to combat sepsis.
Article in Nature medicine, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 34 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
34 citing papers in PubMed, 57 citations in OpenAlex.
- Article
- Article
- A Thrombomodulin Promoter Gene Polymorphism, rs2239562, Influences Both Susceptibility to and Outcome of Sepsis.Frontiers in medicine · 2021Article
- Mucosal-associated invariant T (MAIT) cells mediate protective host responses in sepsis.eLife · 2020Article
- Epigenetic and metabolic programming of innate immunity in sepsis.Innate immunity · 2019Review
- Sirtuins and Immuno-Metabolism of Sepsis.International journal of molecular sciences · 2018Review
- Potential Immunotherapeutics for Immunosuppression in Sepsis.Biomolecules & therapeutics · 2017Review
- Proteome analysis of hemofilter adsorbates to identify novel substances of sepsis: a pilot study.Journal of artificial organs : the official journal of the Japanese Society for Artificial Organs · 2017Article
- Sirtuin 2 Regulates Microvascular Inflammation during Sepsis.Journal of immunology research · 2017Article
- Identification of a novel mechanism of blood-brain communication during peripheral inflammation via choroid plexus-derived extracellular vesicles.EMBO molecular medicine · 2016Article
- Sepsis: in search of cure.Inflammation research : official journal of the European Histamine Research Society ... [et al.] · 2016Review
- Proton pump inhibitors protect mice from acute systemic inflammation and induce long-term cross-tolerance.Cell death & disease · 2016Article
- Abrogating ClC-3 Inhibits LPS-induced Inflammation via Blocking the TLR4/NF-κB Pathway.Scientific reports · 2016Article
- NFI-A disrupts myeloid cell differentiation and maturation in septic mice.Journal of leukocyte biology · 2016Article
- Carbon monoxide in the treatment of sepsis.American journal of physiology. Lung cellular and molecular physiology · 2015Review
- Zinc dyshomeostasis during polymicrobial sepsis in mice involves zinc transporter Zip14 and can be overcome by zinc supplementation.American journal of physiology. Gastrointestinal and liver physiology · 2015Article
- The anti-inflammatory effect of combined complement and CD14 inhibition is preserved during escalating bacterial load.Clinical and experimental immunology · 2015Article
- P2RX7 sensitizes Mac-1/ICAM-1-dependent leukocyte-endothelial adhesion and promotes neurovascular injury during septic encephalopathy.Cell research · 2015Article
- The wingless-related integration site-5a/secreted frizzled-related protein-5 system is dysregulated in human sepsis.Clinical and experimental immunology · 2015Observational
- Sequential actions of SIRT1-RELB-SIRT3 coordinate nuclear-mitochondrial communication during immunometabolic adaptation to acute inflammation and sepsis.The Journal of biological chemistry · 2015Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
1 author.
Funding
No grant is acknowledged in the PubMed record.
Abstract
PubMed holds no abstract for this paper.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.