ArticleJournal of epidemiology and community health1990
Alcohol use in pregnancy, craniofacial features, and fetal growth.
Article in Journal of epidemiology and community health, 1990. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
11 citing papers in PubMed.
- Sexually dimorphic effects of prenatal alcohol exposure on the murine skeleton.Biology of sex differences · 2024Article
- The role of general practitioners in Reunion in detecting alcohol use in pregnant women and identifying fetal alcohol spectrum disorder: a qualitative study.Archives of public health = Archives belges de sante publique · 2023Article
- A systematic review: facial, dental and orthodontic findings and orofacial diagnostics in patients with FASD.Frontiers in pediatrics · 2023Review
- Serum concentrations of IGF-I/IGF-II as biomarkers of alcohol damage during foetal development and diagnostic markers of Foetal Alcohol Syndrome.Scientific reports · 2019Article
- Head circumference at birth and exposure to tobacco, alcohol and illegal drugs during early pregnancy.Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery · 2012Article
- Large-scale analysis of acute ethanol exposure in zebrafish development: a critical time window and resilience.PloS one · 2011Article
- Estimating the prevalence of fetal alcohol syndrome. A summary.Alcohol research & health : the journal of the National Institute on Alcohol Abuse and Alcoholism · 2001Review
- Moderate prenatal alcohol exposure and psychomotor development at preschool age.American journal of public health · 1995Article
- Prenatal alcohol exposure, birthweight, and measures of child size from birth to age 14 years.American journal of public health · 1994Article
- Smoking and drinking habits before and during pregnancy in Spanish women.Journal of epidemiology and community health · 1994Article
- Dysmorphic and anthropometric outcomes in 6-year-old prenatally cocaine-exposed children.Neurotoxicology and teratologyArticle
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
8 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
STUDY
objectiveThe aim was to study the relationship between the level of alcohol consumption in pregnancy and craniofacial characteristics of the neonate.
designThis was a prospective survey of a sample of pregnant women, stratified on prepregnancy level of alcohol consumption.
settingThe study was carried out at the public antenatal clinic of Roubaix maternity hospital.
participantsDuring an eight month period, 684 women (89% of those eligible) were interviewed in a standardised way at their first antenatal clinic visit. Of these, all who were suspected of being alcoholic or heavy drinkers (at least 21 drinks per week) were selected for follow up, as was a subsample of light (0-6 drinks per week) and moderate (7-20 drinks per week) drinkers. Of 347 women selected in this way, 202 had their infants assessed by a standardised morphological examination. MEASUREMENTS AND AND MAIN
resultsSuggestive craniofacial characteristics of the infants, present either in isolation or in association with growth retardation ("fetal alcohol effects"), were compared in relation to maternal alcohol consumption (alcoholic 12%; heavy drinking 24%; moderate drinking 28%; light drinking 36%). No differences were found between light and moderate drinkers. Infants born to alcoholics had a greater number of craniofacial characteristics and the proportion with features compatible with fetal alcohol effects was higher. There was a similar trend for infants of heavy drinkers. Infants of heavy drinkers who had decreased their alcohol consumption during pregnancy had fewer craniofacial features. Infants of heavy smokers were also found to have increased numbers of craniofacial characteristics.
conclusionsCraniofacial morphology could be a sensitive indicator of alcohol exposure in utero. Altered morphology is usually considered specific for alcohol exposure, but the relation observed with smoking needs further exploration.
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