Trial reportJournal of epidemiology and community health1990
Is there a fetal effect with low to moderate alcohol use before or during pregnancy?
Trial report in Journal of epidemiology and community health, 1990. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
12 citing papers in PubMed, 1 synthesis or guideline pooled it, 67 citations in OpenAlex.
- Prevalence and Patterns of Prenatal Alcohol Exposure in Australian Cohort and Cross-Sectional Studies: A Systematic Review of Data Collection Approaches.International journal of environmental research and public health · 2022Pooled it
- The impact of high apparent temperature on spontaneous preterm delivery: a case-crossover study.Environmental health : a global access science source · 2017Article
- Low-to-moderate prenatal alcohol consumption and the risk of selected birth outcomes: a prospective cohort study.Annals of epidemiology · 2015Article
- The effect of different alcohol drinking patterns in early to mid pregnancy on the child's intelligence, attention, and executive function.BJOG : an international journal of obstetrics and gynaecology · 2012Article
- Head circumference at birth and exposure to tobacco, alcohol and illegal drugs during early pregnancy.Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery · 2012Article
- The effect of health compromising behaviors on preterm births.Maternal and child health journal · 2007Article
- Effect of exposure to a country liquor (Toddy) during gestation on lipid metabolism in rats.Plant foods for human nutrition (Dordrecht, Netherlands) · 2001Article
- Estimating the prevalence of fetal alcohol syndrome. A summary.Alcohol research & health : the journal of the National Institute on Alcohol Abuse and Alcoholism · 2001Review
- Prenatal alcohol exposure, birthweight, and measures of child size from birth to age 14 years.American journal of public health · 1994Article
- Smoking and drinking habits before and during pregnancy in Spanish women.Journal of epidemiology and community health · 1994Article
- Knowledge of FAS and the Risks of Heavy Drinking During Pregnancy, 1985 and 1990.Alcohol health and research world · 1994Article
- Cigarette, alcohol, and coffee consumption and prematurity.American journal of public health · 1992Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
STUDY
objectiveThe aim was to investigate the effect of low or moderate alcohol consumption upon fetal outcome.
designThis was a prospective randomised cohort study with mother and infant follow-up sample stratified on level of maternal alcohol intake.
settingA large maternity hospital in Western Australia.
participants2002 randomly selected pregnant women were recruited over a 3 year period for questionnaire survey (19 mothers refused participation). From 665 women in a stratified subsample selected on the basis of prepregnancy alcohol consumption, 605 newborns were available for study. INVESTIGATION AND MAIN
resultsAll 2002 women completed a comprehensive questionnaire on demographic, lifestyle (including diet), health, and obstetric factors. Of the 665 mothers who were followed through pregnancy, 605 liveborns were available at birth for measurement and detailed clinical evaluation. Low to moderate prepregnancy maternal alcohol intake was not associated with any untoward effect upon weight, length, head circumference at birth, or clinical well-being as indicated by Apgar score, respiratory distress syndrome, and overall clinical state. Other factors, particularly nicotine, were of much greater importance.
conclusionsThis study fails to show any significant relationship between low to moderate prepregnancy maternal alcohol intake and newborn clinical status. The outcome suggests that cautionary advice to pregnant women warning that any alcohol taken during pregnancy is potentially harmful to the fetus is inaccurate and therefore probably counterproductive.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.