Evidence map›Paper›PMID 22772437›Full record

ReviewMammalian genome : official journal of the International Mammalian Genome Society2012

Next-generation sequencing of experimental mouse strains.

Binnaz Yalcin, David J Adams, Jonathan Flint, Thomas M Keane

Abstract readReview
In one paragraph

Review in Mammalian genome : official journal of the International Mammalian Genome Society, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 42 papers.

0numbers the graph read from it
0cells of the map it votes in
42citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

42 citing papers in PubMed.

  1. Article
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  9. Comparative genomic analysis of inbred rat strains reveals the existence of ancestral polymorphisms.Mammalian genome : official journal of the International Mammalian Genome Society · 2020
    Article
  10. Article
  11. Article
  12. Article
  13. Article
  14. Tissue-SpecificGenetics · 2019
    Article
  15. Article
  16. Article
  17. Efficient analysis of mouse genome sequences reveal many nonsense variants.Proceedings of the National Academy of Sciences of the United States of America · 2016
    Article
  18. Article
  19. Article
  20. Accessing Data Resources in the Mouse Phenome Database for Genetic Analysis of Murine Life Span and Health Span.The journals of gerontology. Series A, Biological sciences and medical sciences · 2016
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Binnaz YalcinCenter for Integrative Genomics, University of Lausanne, Lausanne, Switzerland. Binnaz.Yalcin@unil.ch
David J Adams
Jonathan Flint
Thomas M Keane

Funding

Cancer Research UK 13031Medical Research Council G0800024Wellcome Trust 090532
6 · The paper itself

Abstract

Since the turn of the century the complete genome sequence of just one mouse strain, C57BL/6J, has been available. Knowing the sequence of this strain has enabled large-scale forward genetic screens to be performed, the creation of an almost complete set of embryonic stem (ES) cell lines with targeted alleles for protein-coding genes, and the generation of a rich catalog of mouse genomic variation. However, many experiments that use other common laboratory mouse strains have been hindered by a lack of whole-genome sequence data for these strains. The last 5 years has witnessed a revolution in DNA sequencing technologies. Recently, these technologies have been used to expand the repertoire of fully sequenced mouse genomes. In this article we review the main findings of these studies and discuss how the sequence of mouse genomes is helping pave the way from sequence to phenotype. Finally, we discuss the prospects for using de novo assembly techniques to obtain high-quality assembled genome sequences of these laboratory mouse strains, and what advances in sequencing technologies may be required to achieve this goal.

Indexed as

AnimalsCell LineEmbryonic Stem CellsMiceMice, Inbred C57BL

Identifiers

PMID22772437
PMCPMC3463794

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.