Evidence map›Paper›PMID 22772149›Full record

ArticleEuropean radiology2013

Standalone computer-aided detection compared to radiologists' performance for the detection of mammographic masses.

Rianne Hupse, Maurice Samulski, Marc Lobbes, Ard den Heeten, Mechli W Imhof-Tas, David Beijerinck, Ruud Pijnappel, Carla Boetes, Nico Karssemeijer

Abstract readComparative Study
PubMed Publisher
In one paragraph

Article in European radiology, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed, 1 pooled it
1.3field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 1 synthesis or guideline pooled it, 22 citations in OpenAlex.

  1. Pooled it
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 4 institutions in 1 country.

Rianne HupseDepartment of Radiology, Radboud University Nijmegen Medical Centre, Nijmegen, The Netherlands. a.hupse@rad.umcn.nl
Maurice Samulski
Marc Lobbes
Ard den Heeten
Mechli W Imhof-Tas
David Beijerinck
Ruud Pijnappel
Carla Boetes
Nico Karssemeijer
Radboud University Medical Center · NLMaastricht University Medical Centre · NLAcademic Medical Center · NLDutch Expert Centre for Screening · NL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivesWe developed a computer-aided detection (CAD) system aimed at decision support for detection of malignant masses and architectural distortions in mammograms. The effect of this system on radiologists' performance depends strongly on its standalone performance. The purpose of this study was to compare the standalone performance of this CAD system to that of radiologists.

methodsIn a retrospective study, nine certified screening radiologists and three residents read 200 digital screening mammograms without the use of CAD. Performances of the individual readers and of CAD were computed as the true-positive fraction (TPF) at a false-positive fraction of 0.05 and 0.2. Differences were analysed using an independent one-sample t-test.

resultsAt a false-positive fraction of 0.05, the performance of CAD (TPF = 0.487) was similar to that of the certified screening radiologists (TPF = 0.518, P = 0.17). At a false-positive fraction of 0.2, CAD performance (TPF = 0.620) was significantly lower than the radiologist performance (TPF = 0.736, P <0.001). Compared to the residents, CAD performance was similar for all false-positive fractions.

conclusionsThe sensitivity of CAD at a high specificity was comparable to that of human readers. These results show potential for CAD to be used as an independent reader in breast cancer screening.

Indexed as

Clinical CompetenceAgedBreast NeoplasmsDecision Support Systems, ClinicalFalse Negative ReactionsFalse Positive ReactionsFemaleHumansMammographyMass ScreeningMiddle AgedNetherlandsRadiographic Image Interpretation, Computer-AssistedRetrospective StudiesSensitivity and Specificity

Identifiers

PMID22772149
OpenAlexW1986713548

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.