Evidence map›Paper›PMID 22772037›Full record

ArticleArtificial DNA, PNA & XNA

Introduction of multiphosphonate ligand to peptide nucleic acid for metal ion conjugation.

Yuichiro Aiba, Yuta Honda, Yue Han, Makoto Komiyama

Abstract read
In one paragraph

Article in Artificial DNA, PNA & XNA. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Yuichiro AibaResearch Center for Advanced Science and Technology; The University of Tokyo, Tokyo, Japan.
Yuta Honda
Yue Han
Makoto Komiyama

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Peptide nucleic acid (PNA) is one of the most widely used synthetic DNA analogs. Conjugation of functional molecules to PNA is very effective to further widen its potential applications. For this purpose, here we report the synthesis of several ligand monomers and introduced them to PNA. These ligand-modified PNAs attract cerium ion and are useful for site-selective DNA hydrolysis. It should be noted that these ligands on PNA are also effective even under the conditions of invasion complex.

Indexed as

Base SequenceCeriumChelating AgentsDNA CleavageLigandsOrganophosphonatesPeptide Nucleic AcidsSubstrate SpecificityCeriumChelating AgentsLigandsOrganophosphonatesPeptide Nucleic Acids

Identifiers

PMID22772037
PMCPMC3429533

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.