Evidence map›Paper›PMID 22771992›Full record

ReviewTranscription

σ70 and PhoB activator: getting a better grip.

Albert Canals, Alexandre G Blanco, Miquel Coll

Abstract readReview
In one paragraph

Review in Transcription. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Article
  2. Genome-wide mapping of thebioRxiv : the preprint server for biology · 2023
    Article
  3. Review
  4. Control of theEcoSal Plus · 2019
    Review
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Albert CanalsInstitute for Research in Biomedicine, Barcelona, Spain.
Alexandre G Blanco
Miquel Coll

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Transcription factors modulate gene expression by distinct, barely understood mechanisms. The crystal structure of a bacterial transcription subcomplex comprising the effector domain of factor PhoB, its target DNA and the σ4 domain of the RNA polymerase σ70 subunit supports the notion that a stronger grip on the promoter-factor complex results in an enhanced RNAP architecture.

Indexed as

Bacterial ProteinsDNA, BacterialDNA-Directed RNA PolymerasesEscherichia coliPromoter Regions, GeneticProtein BindingSigma FactorTranscriptional ActivationTranscription FactorsTranscription, GeneticBacterial ProteinsDNA, BacterialDNA-Directed RNA PolymerasesPhoB protein, BacteriaRNA polymerase sigma 70Sigma FactorTranscription Factors

Identifiers

PMID22771992
PMCPMC3654763

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.