Evidence map›Paper›PMID 22771989›Full record

ArticleTranscription

Gdown1: making a link between mediator and RNA polymerase II elongation control.

Tiandao Li, David Price

Abstract read
In one paragraph

Article in Transcription. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Review
  6. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Tiandao LiUniversity of Iowa, Iowa City, IA, USA.
David Price

Funding

FACTORS INVOLVED IN TRANSCRIPTION BY RNA POLYMERSASE IIR01GM035500 · NIGMS · UNIVERSITY OF IOWA · PI PRICE, DAVID H · 1985 to 2017
$6.5M
NIGMS NIH HHS GM35500NIGMS NIH HHS R01 GM035500
6 · The paper itself

Abstract

Gdown1 is a substoichiometric RNA polymerase II subunit that modulates effects of both Mediator and elongation factors in vitro and is broadly distributed across the human genome. Here we assemble the existing information on Gdown1, provide additional bioinformatics analyses, and propose a working model for Gdown1 function.

Indexed as

AnimalsComputational BiologyHumansModels, BiologicalRNA Polymerase IITranscription Elongation, GeneticPOLR2M protein, humanRNA Polymerase II

Identifiers

PMID22771989
PMCPMC3654766

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.