ReviewClinical immunology (Orlando, Fla.)2012
Humoral innate immune response and disease.
Review in Clinical immunology (Orlando, Fla.), 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 35 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
35 citing papers in PubMed, 89 citations in OpenAlex.
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- Immune functions of pattern recognition receptors in Lepidoptera.Frontiers in immunology · 2023Review
- The role of the adaptive immune system and T cell dysfunction in neurodegenerative diseases.Journal of neuroinflammation · 2022Review
- Succinate and inosine coordinate innate immune response to bacterial infection.PLoS pathogens · 2022Article
- Proteostasis Perturbations and Their Roles in Causing Sterile Inflammation and Autoinflammatory Diseases.Cells · 2022Review
- Germline determinants of humoral immune response to HPV-16 protect against oropharyngeal cancer.Nature communications · 2021Article
- Systemic antiviral immunization by virus-mimicking nanoparticles-decorated erythrocytes.Nano today · 2021Article
- Development and Evaluation of an Ebola Virus Glycoprotein Mucin-Like Domain Replacement System as a New Dendritic Cell-Targeting Vaccine Approach against HIV-1.Journal of virology · 2021Article
- Enhancing oxygenation of patients with coronavirus disease 2019: Effects on immunity and other health-related conditions.World journal of clinical cases · 2021Review
- Dual RNAseq highlights the kinetics of skin microbiome and fish host responsiveness to bacterial infection.Animal microbiome · 2021Article
- Article
- A Thioester-Containing Protein Controls Dengue Virus Infection inFrontiers in immunology · 2021Article
- Necrotizing Bacterial Myositis as the Initial Presentation of Severe Aplastic Anaemia.Case reports in hematology · 2021Article
- Convalescent Plasma for the Treatment of Severe COVID-19 Infection in Cancer Patients.Cancer medicine · 2020Article
- A Single Human VCell reports · 2020Article
- Microalgae with Immunomodulatory Activities.Marine drugs · 2019Review
- Immunogenicity of Protein Pharmaceuticals.Journal of pharmaceutical sciences · 2019Review
- Hyaluronan interactions with innate immunity in lung biology.Matrix biology : journal of the International Society for Matrix Biology · 2019Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors at 1 institution in 1 country.
Funding
Abstract
The humoral innate immune response consists of multiple components, including the naturally occurring antibodies (NAb), pentraxins and the complement and contact cascades. As soluble, plasma components, these innate proteins provide key elements in the prevention and control of disease. However, pathogens and cells with altered self proteins utilize multiple humoral components to evade destruction and promote pathology. Many studies have examined the relationship between humoral immunity and autoimmune disorders. This review focuses on the interactions between the humoral components and their role in promoting the pathogenesis of bacterial and viral infections and chronic diseases such as atherosclerosis and cancer. Understanding the beneficial and detrimental aspects of the individual components and the interactions between proteins which regulate the innate and adaptive response will provide therapeutic targets for subsequent studies.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.