ArticleAmerican journal of epidemiology2012
Parent-offspring body mass index associations in the Norwegian Mother and Child Cohort Study: a family-based approach to studying the role of the intrauterine environment in childhood adiposity.
Article in American journal of epidemiology, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 55 papers, 5 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
55 citing papers in PubMed, 5 syntheses or guidelines pooled it.
- The Relationship Between Paternal Smoking and Overweight/Obesity with Childhood Overweight/Obesity: A Systematic Review.Current obesity reports · 2025Pooled it
- Body mass index in parents and their adult offspring: A systematic review and meta-analysis.Obesity reviews : an official journal of the International Association for the Study of Obesity · 2024Pooled it
- Paternal preconception modifiable risk factors for adverse pregnancy and offspring outcomes: a review of contemporary evidence from observational studies.BMC public health · 2023Pooled it
- The association between maternal body mass index and child obesity: A systematic review and meta-analysis.PLoS medicine · 2019Pooled it
- Maternal BMI at the start of pregnancy and offspring epigenome-wide DNA methylation: findings from the pregnancy and childhood epigenetics (PACE) consortium.Human molecular genetics · 2017Pooled it
- Associations Between Paternal Pre-Conceptional Body Mass Index and Lifestyle Factors and Offspring Weight Development.Pediatric obesity · 2026Trial
- Adiposity and cardiovascular outcomes in three-year-old children of participants in UPBEAT, an RCT of a complex intervention in pregnant women with obesity.Pediatric obesity · 2021Trial
- Trial
- Parental body mass index and offspring childhood body size and eating behaviour: A structural equation modelling analysis in the Norwegian Mother, Father and Child Cohort Study.PLoS medicine · 2026Article
- Determining the interplay of prenatal parental BMI in shaping child BMI trajectories: the CHILD Cohort Study.International journal of obesity (2005) · 2025Article
- Nutritional counselling and risk factors for obesity: an observational study in toddlers.Italian journal of pediatrics · 2024Observational
- The role of fathers in child development from preconception to postnatal influences: Opportunities for the National Institutes of Health Environmental influences on Child Health Outcomes (ECHO) program.Developmental psychobiology · 2024Review
- Parent-Offspring Associations of Ideal Cardiovascular Health Metrics: Findings From the 2014 to 2021 Korea National Health and Nutrition Examination Survey.Journal of the American Heart Association · 2024Article
- Child and adolescent obesity.Nature reviews. Disease primers · 2023Review
- Comparison of intergenerational instrumental variable analyses of body mass index and mortality in UK Biobank.International journal of epidemiology · 2023Article
- Paternal BMI in the preconception period, and the association with child zBMI.International journal of obesity (2005) · 2023Article
- Exploring the causal effect of maternal pregnancy adiposity on offspring adiposity: Mendelian randomisation using polygenic risk scores.BMC medicine · 2022Article
- Do genetic risk scores for childhood adiposity operate independent of BMI of their mothers?International journal of obesity (2005) · 2021Article
- Association between parental and offspring BMI: results from EPACI Portugal 2012.Public health nutrition · 2021Article
- Epigenetic changes on rat chromosome 4 contribute to disparate alcohol drinking behavior in alcohol-preferring and -nonpreferring rats.Alcohol (Fayetteville, N.Y.) · 2020Article
Corrections and comments
- Commented on by
Authors and funding
7 authors.
Funding
Abstract
In the present study, the authors investigated the role of the intrauterine environment in childhood adiposity by comparing the maternal-offspring body mass index (BMI) association with the paternal-offspring BMI association when the offspring were 3 years of age, using parental prepregnancy BMI (measured as weight in kilograms divided by height in meters squared). The parent-offspring trios (n = 29,216) were recruited during pregnancy from 2001 to 2008 into the Norwegian Mother and Child Cohort Study conducted by The Norwegian Institute of Public Health. Data from self-administered questionnaires were used in linear regression analyses. Crude analyses showed similar parental-offspring BMI associations; the mean difference in offspring BMI was 0.15 (95% confidence interval: 0.13, 0.16) per each 1-standard-deviation increase in maternal BMI and 0.15 (95% confidence interval: 0.13, 0.17) per each 1-standard-deviation increase in paternal BMI. After all adjustments, the mean difference in offspring BMI per each 1-standard-deviation increment of maternal BMI was 0.12, and the mean difference in offspring BMI per each 1-standard-deviation increment of paternal BMI was 0.13. There was no strong support for heterogeneity between the associations (P > 0.6). In conclusion, results from the present large population-based study showed similar parental-offspring BMI associations when the offspring were 3 years of age, which indicates that the maternal-offspring association may be explained by shared familial (environmental and genetic) risk factors rather than by the intrauterine environment.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.