Evidence map›Paper›PMID 22770229›Full record

ArticleDiagnostic pathology2012

Peripheral T-cell Lymphoma with Cyclin D1 overexpression: a case report.

Gabriella Aquino, Renato Franco, Fioravante Ronconi, Annamaria Anniciello, Luigi Russo, Annarosaria De Chiara, Luigi Panico

Open access · goldAbstract readCase Reports
In one paragraph

Article in Diagnostic pathology, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
1.6field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 12 citations in OpenAlex.

  1. Cyclin D1 expression in prostate carcinoma.Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologica · 2014
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 1 country.

Gabriella AquinoPathology Unit, National Cancer Institute Fondazione Giovanni Pascale, Via Mariano Semmola, 80131 Napoli, Italy.
Renato Franco
Fioravante Ronconi
Annamaria Anniciello
Luigi Russo
Annarosaria De Chiara
Luigi Panico
Istituto Nazionale Tumori IRCCS "Fondazione G. Pascale" · ITAzienda Ospedaliera S.Giuseppe Moscati · ITFatebenefratelli Hospital · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Peripheral T-cell lymphomas not otherwise specified are generally considered aggressive non-Hodgkin lymphomas, because of poor natural outcome and response to therapy. They show a complex karyotype without any specific genetic hallmark. We report a case of peripheral T-cell lymphoma not otherwise specified with heterogeneous nuclear cyclin D1 immunohistochemical overexpression, due to gene copy gain, a phenomenon similar to that observed in mantle cell lymphoma characterized by t(11;14)(q13;q32). In this case report we underline the diagnostic pitfall represented by cyclin D1 immunohistochemical overexpression in a T-cell lymphoma. Several pitfalls could lead to misinterpretation of diagnosis, therefore, we underlined the need to integrate the classical histology and immunohistochemistry with molecular tests as clonality or fluorescence in situ hybridization. VIRTUAL SLIDE: The virtual slides for this article can be found here: http://www.diagnosticpathology.diagnomx.eu/vs/1117747619703769.

Indexed as

AgedAntineoplastic Combined Chemotherapy ProtocolsBiomarkers, TumorBiopsyCell ProliferationCyclin D1DeoxycytidineDiagnostic ErrorsFatal OutcomeGene DosageGene Expression Regulation, NeoplasticHumansImmunohistochemistryImmunophenotypingIn Situ Hybridization, FluorescenceLymphoma, Mantle-CellBiomarkers, TumorCCND1 protein, humanCyclin D1DeoxycytidineOrganoplatinum Compounds

Identifiers

PMID22770229
PMCPMC3475098
OpenAlexW1982814490

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.