ArticleBiophysical journal2012
Dynamics of freely oscillating and coupled hair cell bundles under mechanical deflection.
Article in Biophysical journal, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
16 citing papers in PubMed.
- How Exceptional Is the Ear?Journal of the Association for Research in Otolaryngology : JARO · 2025Review
- Criticality and chaos in auditory and vestibular sensing.Scientific reports · 2024Article
- Vestibular Drop Attacks and Meniere's Disease as Results of Otolithic Membrane Damage-A Numerical Model.Journal of the Association for Research in Otolaryngology : JARO · 2023Article
- Complex dynamics of hair bundle of auditory nervous system (II): forced oscillations related to two cases of steady state.Cognitive neurodynamics · 2022Article
- Unloading outer hair cell bundles in vivo does not yield evidence of spontaneous oscillations in the mouse cochlea.Hearing research · 2022Article
- Complex dynamics of hair bundle of auditory nervous system (I): spontaneous oscillations and two cases of steady states.Cognitive neurodynamics · 2022Article
- Modeling the tonotopic map using a two-dimensional array of neural oscillators.Frontiers in computational neuroscience · 2022Article
- A Bundle of Mechanisms: Inner-Ear Hair-Cell Mechanotransduction.Trends in neurosciences · 2019Review
- Influence of Magnitude and Duration of Altered Gravity and Readaptation to 1 g on the Structure and Function of the Utricle in Toadfish,Frontiers in physiology · 2018Article
- Electrophysiological Measurements of Peripheral Vestibular Function-A Review of Electrovestibulography.Frontiers in systems neuroscience · 2017Review
- High-order synchronization of hair cell bundles.Scientific reports · 2016Article
- Identification of Bifurcations from Observations of Noisy Biological Oscillators.Biophysical journal · 2016Article
- Voltage-Mediated Control of Spontaneous Bundle Oscillations in Saccular Hair Cells.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2015Article
- Control of a hair bundle's mechanosensory function by its mechanical load.Proceedings of the National Academy of Sciences of the United States of America · 2015Article
- Mechanical amplification exhibited by quiescent saccular hair bundles.Biophysical journal · 2015Article
- Phase-locked spiking of inner ear hair cells and the driven noisy Adler equation.Interface focus · 2014Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors.
Funding
Abstract
In vitro, attachment to the overlying membrane was found to affect the resting position of the hair cell bundles of the bullfrog sacculus. To assess the effects of such a deflection on mechanically decoupled hair bundles, comparable offsets were imposed on decoupled spontaneously oscillating bundles. Strong modulation was observed in their dynamic state under deflection, with qualitative changes in the oscillation profile, amplitude, and characteristic frequency of oscillation seen in response to stimulus. Large offsets were found to arrest spontaneous oscillation, with subsequent recovery upon reversal of the stimulus. The dynamic state of the hair bundle displayed hysteresis and a dependence on the direction of the imposed offset. The coupled system of hair bundles, with the overlying membrane left on top of the preparation, also exhibited a dependence on offset position, with an increase in the linear response function observed under deflections in the inhibitory direction.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.