ReviewJournal of diabetes science and technology2012
Resting blood flow in the skin: does it exist, and what is the influence of temperature, aging, and diabetes?
Review in Journal of diabetes science and technology, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
12 citing papers in PubMed, 1 synthesis or guideline pooled it, 45 citations in OpenAlex.
- Does the ultrasound imaging predict lower limb tendinopathy in athletes: a systematic review.BMC medical imaging · 2023Pooled it
- Trial
- Pressure-Induced Microvascular Reactivity With Whole Foot Loading Is Unique Across the Human Foot Sole.Microcirculation (New York, N.Y. : 1994) · 2025Article
- Mechanoreceptor sensory feedback is impaired by pressure induced cutaneous ischemia on the human foot sole and can predict cutaneous microvascular reactivity.Frontiers in neuroscience · 2024Article
- Mechanically and physiologically optimizing prosthetic elevated vacuum systems in people with transtibial amputation: a pilot study.Journal of prosthetics and orthotics : JPO · 2022Article
- Continuous monitoring of deep-tissue haemodynamics with stretchable ultrasonic phased arrays.Nature biomedical engineering · 2021Article
- High Precision Human Skin Temperature Fluctuations Measuring Instrument.Sensors (Basel, Switzerland) · 2021Article
- In vivo skin thermophysical property testing technology using flexible thermosensor-based 3International journal of heat and mass transfer · 2020Article
- Systemic and Local Effects of Warm Oxygen Exposure to the Lower Extremities in Healthy Volunteers.Journal of clinical and diagnostic research : JCDR · 2017Article
- Epidermal devices for noninvasive, precise, and continuous mapping of macrovascular and microvascular blood flow.Science advances · 2015Article
- Effect of heat, cold, and pressure on the transverse carpal ligament and median nerve: a pilot study.Medical science monitor : international medical journal of experimental and clinical research · 2015Article
- What is more damaging to vascular endothelial function: Diabetes, age, high BMI, or all of the above?Medical science monitor : international medical journal of experimental and clinical research · 2013Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
1 author at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Measurement of resting blood flow to the skin and other organs is an important indicator of health and disease and a way to assess the reaction to various stimuli and pharmaceutical interventions. However, unlike plasma ions such as sodium or potassium, it is difficult to determine what the proper value for resting blood flow really is. Part of the problem is in the measurement of blood flow; various techniques yield very different measures of skin blood flow even in the same area. Even if there were common techniques, resting blood flow to tissue, such as the skin, is determined by the interaction of a plurality of factors, including the sympathetic nervous system, temperature, pressure, shear forces on blood vessels, tissue osmolality, and a variety of other stimuli. Compounding this variability, the blood flow response to any stressor is reduced by free radicals in the blood and diminished by aging and diabetes. Race also has an effect on resting blood flow to the skin. All these factors interact to make the exact resting blood flow difficult to determine in any one individual and at any one time. This review examines the main techniques to assess blood flow, the factors that alter blood flow in the skin, and how aging and diabetes affect blood flow. Recommendations for the measurement of resting blood flow are presented.
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Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.