ArticlePloS one2012
Characterization of miRNAs in response to short-term waterlogging in three inbred lines of Zea mays.
Article in PloS one, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 49 papers.
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Who cites it
49 citing papers in PubMed, 113 citations in OpenAlex.
- Stu-miR393-5p-StTIR1A-StPLC2 module regulates the development of adventitious and lateral roots of potato.Plant cell reports · 2026Article
- Identification and functional validation of hub genes responding to waterlogging stress during the filling period in quinoa (Chenopodium Quinoa Willd.).BMC plant biology · 2026Article
- MicroRNA528 and Its Regulatory Roles in Monocotyledonous Plants.International journal of molecular sciences · 2025Review
- In Silico Genome-Wide Profiling of Conserved miRNAs in AAA, AAB, and ABB Groups ofInternational journal of molecular sciences · 2025Article
- Decoding plant responses to waterlogging: from stress signals to molecular mechanisms and their future implications.Plant molecular biology · 2025Review
- Physiological and Multi-Omics Integrative Analysis Provides New Insights into Tolerance to Waterlogging Stress in Sesame (International journal of molecular sciences · 2025Article
- A review of soil waterlogging impacts, mechanisms, and adaptive strategies.Frontiers in plant science · 2025Review
- Characterization of the Regulatory Network under Waterlogging Stress in Soybean Roots via Transcriptome Analysis.Plants (Basel, Switzerland) · 2024Article
- Spatial heterogeneity in the properties of hydroponic wheat fodder and its sustainability.Scientific reports · 2024Article
- Application of multiomics analysis to plant flooding response.Frontiers in plant science · 2024Review
- Response to Cadmium Toxicity: Orchestration of Polyamines and microRNAs in Maize Plant.Plants (Basel, Switzerland) · 2023Article
- The miR393-Target Module Regulates Plant Development and Responses to Biotic and Abiotic Stresses.International journal of molecular sciences · 2022Review
- Meta-QTL analysis and candidate genes identification for various abiotic stresses in maize (Molecular breeding : new strategies in plant improvement · 2022Article
- Genome-Wide Association Study Reveals Marker Trait Associations (MTA) for Waterlogging-Triggered Adventitious Roots and Aerenchyma Formation in Barley.International journal of molecular sciences · 2022Article
- Transcriptome analysis revealed the expression levels of genes related to abscisic acid and auxin biosynthesis in grapevine (Frontiers in plant science · 2022Article
- miRNAs play critical roles in response to abiotic stress by modulating cross-talk of phytohormone signaling.Plant cell reports · 2021Review
- Transcriptome Analysis Reveals Genes of Flooding-Tolerant and Flooding-Sensitive Rapeseeds Differentially Respond to Flooding at the Germination Stage.Plants (Basel, Switzerland) · 2021Article
- MicroRNAs: Potential Targets for Developing Stress-Tolerant Crops.Life (Basel, Switzerland) · 2021Review
- Differential Expression of Maize and Teosinte microRNAs under Submergence, Drought, and Alternated Stress.Plants (Basel, Switzerland) · 2020Article
- Current breeding and genomic approaches to enhance the cane and sugar productivity under abiotic stress conditions.3 Biotech · 2020Review
Corrections and comments
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Authors and funding
5 authors at 3 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Waterlogging of plants leads to low oxygen levels (hypoxia) in the roots and causes a metabolic switch from aerobic respiration to anaerobic fermentation that results in rapid changes in gene transcription and protein synthesis. Our research seeks to characterize the microRNA-mediated gene regulatory networks associated with short-term waterlogging. MicroRNAs (miRNAs) are small non-coding RNAs that regulate many genes involved in growth, development and various biotic and abiotic stress responses. To characterize the involvement of miRNAs and their targets in response to short-term hypoxia conditions, a quantitative real time PCR (qRT-PCR) assay was used to quantify the expression of the 24 candidate mature miRNA signatures (22 known and 2 novel mature miRNAs, representing 66 miRNA loci) and their 92 predicted targets in three inbred Zea mays lines (waterlogging tolerant Hz32, mid-tolerant B73, and sensitive Mo17). Based on our studies, miR159, miR164, miR167, miR393, miR408 and miR528, which are mainly involved in root development and stress responses, were found to be key regulators in the post-transcriptional regulatory mechanisms under short-term waterlogging conditions in three inbred lines. Further, computational approaches were used to predict the stress and development related cis-regulatory elements on the promoters of these miRNAs; and a probable miRNA-mediated gene regulatory network in response to short-term waterlogging stress was constructed. The differential expression patterns of miRNAs and their targets in these three inbred lines suggest that the miRNAs are active participants in the signal transduction at the early stage of hypoxia conditions via a gene regulatory network; and crosstalk occurs between different biochemical pathways.
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