ArticleIntegrative and comparative biology2012
Coral comparative genomics reveal expanded Hox cluster in the cnidarian-bilaterian ancestor.
Article in Integrative and comparative biology, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.
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20 citing papers in PubMed, 51 citations in OpenAlex.
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- The genome of the deep-sea anemoneProceedings. Biological sciences · 2023Article
- Genetic adaptations of sea anemone to hydrothermal environment.Science advances · 2023Article
- Gene Loss may have Shaped the Cnidarian and Bilaterian Hox and ParaHox Complement.Genome biology and evolution · 2023Article
- Seeking Sense in the Hox Gene Cluster.Journal of developmental biology · 2022Review
- Emergence of distinct syntenic density regimes is associated with early metazoan genomic transitions.BMC genomics · 2022Article
- Transcriptional characterisation of the Exaiptasia pallida pedal disc.BMC genomics · 2019Article
- "Dorsal-Ventral" Genes Are Part of an Ancient Axial Patterning System: Evidence from Trichoplax adhaerens (Placozoa).Molecular biology and evolution · 2019Article
- The genome of the giant Nomura's jellyfish sheds light on the early evolution of active predation.BMC biology · 2019Article
- Comparative genomics reveals the distinct evolutionary trajectories of the robust and complex coral lineages.Genome biology · 2018Article
- Hox and Wnt pattern the primary body axis of an anthozoan cnidarian before gastrulation.Nature communications · 2018Article
- Non-specificity of transcription factor function in Drosophila melanogaster.Development genes and evolution · 2017Article
- Developmental Progression in the Coral Acropora digitifera Is Controlled by Differential Expression of Distinct Regulatory Gene Networks.Genome biology and evolution · 2016Article
- From nerve net to nerve ring, nerve cord and brain--evolution of the nervous system.Nature reviews. Neuroscience · 2016Review
- The genome of Aiptasia, a sea anemone model for coral symbiosis.Proceedings of the National Academy of Sciences of the United States of America · 2015Article
- Evolution of transcription factor function as a mechanism for changing metazoan developmental gene regulatory networks.EvoDevo · 2015Review
- Article
- A genomic approach to coral-dinoflagellate symbiosis: studies of Acropora digitifera and Symbiodinium minutum.Frontiers in microbiology · 2014Review
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Authors and funding
5 authors at 3 institutions in 3 countries.
Funding
Abstract
The key developmental role of the Hox cluster of genes was established prior to the last common ancestor of protostomes and deuterostomes and the subsequent evolution of this cluster has played a major role in the morphological diversity exhibited in extant bilaterians. Despite 20 years of research into cnidarian Hox genes, the nature of the cnidarian-bilaterian ancestral Hox cluster remains unclear. In an attempt to further elucidate this critical phylogenetic node, we have characterized the Hox cluster of the recently sequenced Acropora digitifera genome. The A. digitifera genome contains two anterior Hox genes (PG1 and PG2) linked to an Eve homeobox gene and an Anthox1A gene, which is thought to be either a posterior or posterior/central Hox gene. These data show that the Hox cluster of the cnidarian-bilaterian ancestor was more extensive than previously thought. The results are congruent with the existence of an ancient set of constraints on the Hox cluster and reinforce the importance of incorporating a wide range of animal species to reconstruct critical ancestral nodes.
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