Trial reportHNO2012
[Development and validation of the Tonsillectomy Outcome Inventory 14].
Trial report in HNO, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers, 2 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
20 citing papers in PubMed, 2 syntheses or guidelines pooled it, 32 citations in OpenAlex.
- Quality of life after tonsillectomy in adult patients with recurrent acute tonsillitis: a systematic review.European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery · 2022Pooled it
- Structured literature review of patient-reported outcome (PRO) instruments in adult tonsillectomy or tonsillotomy.Health and quality of life outcomes · 2019Pooled it
- Piloting of a Decision Aid for Recurrent Tonsillitis.Clinical otolaryngology : official journal of ENT-UK ; official journal of Netherlands Society for Oto-Rhino-Laryngology & Cervico-Facial Surgery · 2025Trial
- Tonsillectomy compared with conservative management in patients over 16 years with recurrent sore throat: the NATTINA RCT and economic evaluation.Health technology assessment (Winchester, England) · 2023Trial
- Trial
- Trial
- How Does the Morbidity of Sore Throat in Recurrent Tonsillitis Correlate With the Tonsillitis Outcome Inventory-14 (TOI-14)?Clinical otolaryngology : official journal of ENT-UK ; official journal of Netherlands Society for Oto-Rhino-Laryngology & Cervico-Facial Surgery · 2026Article
- Adult BiZact Tonsillectomy: A Prospective Multicenter Study of Outcomes and Patient-Reported Recovery.Laryngoscope investigative otolaryngology · 2026Article
- Validation and Clinical Adaptation of a Swedish Version of the Tonsil Outcome Inventory-14 Questionnaire.Laryngoscope investigative otolaryngology · 2026Article
- Does a tonsillectomy indicated according to the German S2k guideline affect short-term quality of life in adults?European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery · 2023Article
- Treatment of recurrent acute tonsillitis-a systematic review and clinical practice recommendations.Frontiers in surgery · 2023Review
- Article
- Article
- Increased levels of S100A8/A9, IL-1ß and IL-18 as a novel biomarker for recurrent tonsillitis.Journal of inflammation (London, England) · 2021Article
- Normative tonsillectomy outcome inventory 14 values as a decision-making tool for tonsillectomy.European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery · 2021Article
- Interpretation of Tonsillectomy Outcome Inventory-14 scores: a prospective matched cohort study.European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery · 2020Article
- The effect of tonsillectomy on the morbidity from recurrent tonsillitis.Clinical otolaryngology : official journal of ENT-UK ; official journal of Netherlands Society for Oto-Rhino-Laryngology & Cervico-Facial Surgery · 2017Observational
- Quality of life in functional rhinoplasty: rhinoplasty outcomes evaluation German version (ROE-D).European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery · 2016Article
- Evidence gaps in ENT surgery - a qualitative survey.GMS current topics in otorhinolaryngology, head and neck surgery · 2016Review
- Evaluation of a German version of the tonsil and adenoid health status instrument.Journal of otolaryngology - head & neck surgery = Le Journal d'oto-rhino-laryngologie et de chirurgie cervico-faciale · 2014Article
Corrections and comments
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Authors and funding
4 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundUntil now, no validated instrument to measure disease-specific, health-related quality of life (HR-QOL) in adults with chronic tonsillitis (CTO) exists. MATERIAL AND
methodsAfter an item reduction of the alpha-version of the Tonsillectomy Outcome Inventory (TOI), the TOI-14 resulted. In addition to the total score, it includes the subscales throat problems, overall health, resources, and social-psychological restrictions. In phase 2, the TOI-14 was prospectively validated on 108 adults with CTO, who had undergone a tonsillectomy.
resultsThe TOI-14 had, on average, good reliability. It included all important aspects of the HR-QOL. Patients with CTO can be distinguished with high sensitivity from healthy subjects. All scores showed moderate to good correlation with the subjective limitation in quality of life. The sensitivity of the questionnaire demonstrated major effects postoperatively.
conclusionThe TOI-14 constitutes the first worldwide-validated, disease-specific instrument to measure HR-QOL in adults with CTO. Due to its ease of use, it can be utilized both in the outcome research and in clinical routine.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.