Evidence map›Paper›PMID 22767141›Full record

ReviewInternational journal of hematology2012

Severe thrombocytopenia and alveolar hemorrhage represent two types of bleeding tendency during tirofiban treatment: case report and literature review.

Omer Celal Elcioglu, Abdullah Ozkok, Timur Selcuk Akpınar, Fatih Tufan, Murat Sezer, Sabahattin Umman, Sevgi Kalayoglu Besısık

Abstract readCase ReportsReview
PubMed Publisher
In one paragraph

Review in International journal of hematology, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
0.9field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 18 citations in OpenAlex.

  1. Trial
  2. Article
  3. Article
  4. Tirofiban-induced thrombocytopenia.Annals of medicine · 2023
    Review
  5. Article
  6. Article
  7. Article
  8. Article
  9. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Omer Celal ElciogluDepartment of Internal Medicine, Istanbul University, Istanbul Faculty of Medicine, Fatih, 34390 Istanbul, Turkey. o.c.elcioglu@gmail.com
Abdullah Ozkok
Timur Selcuk Akpınar
Fatih Tufan
Murat Sezer
Sabahattin Umman
Sevgi Kalayoglu Besısık
Istanbul University · TR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Tirofiban is a glycoprotein (GP) IIb/IIIa receptor antagonist used in the treatment of acute coronary syndrome (ACS). Thrombocytopenia is a well-known complication of GPIIb/IIIa inhibitors. Life-threatening complications such as alveolar and gastrointestinal system hemorrhages may occur in the course of thrombocytopenia. Platelet count should be monitored closely, including during the first few hours of the infusion. Adverse events may be prevented by prompt discontinuation of the therapy. Herein we present two cases of profound and sudden thrombocytopenia associated with tirofiban use in the treatment of ACS together with a review of the literature.

Indexed as

Acute Coronary SyndromeAgedHemorrhageHumansMaleMiddle AgedPlatelet CountPlatelet Glycoprotein GPIIb-IIIa ComplexPulmonary AlveoliThrombocytopeniaTirofibanTyrosinePlatelet Glycoprotein GPIIb-IIIa ComplexTirofibanTyrosine

Identifiers

PMID22767141
OpenAlexW1985410128

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.