SynthesisJournal of gastrointestinal surgery : official journal of the Society for Surgery of the Alimentary Tract2012
Meta-analysis of prospective randomized studies comparing single-incision laparoscopic cholecystectomy (SILC) and conventional multiport laparoscopic cholecystectomy (CMLC).
Synthesis in Journal of gastrointestinal surgery : official journal of the Society for Surgery of the Alimentary Tract, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 47 papers, 10 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
47 citing papers in PubMed, 10 syntheses or guidelines pooled it, 101 citations in OpenAlex.
- Comparison of single-incision and traditional laparoscopic surgery for the risk of incisional hernia: a systematic review and meta-analysis of randomized controlled trials.Updates in surgery · 2026Pooled it
- Laparoscopic surgery and robotic surgery for single-incision cholecystectomy: an updated systematic review.Updates in surgery · 2021Pooled it
- Incidence of incisional hernias following single-incision versus traditional laparoscopic surgery: a meta-analysis.Hernia : the journal of hernias and abdominal wall surgery · 2019Pooled it
- Safety of single-incision robotic cholecystectomy for benign gallbladder disease: a systematic review.Surgical endoscopy · 2018Pooled it
- Single-incision laparoscopic cholecystectomy: does it work? A systematic review.Surgical endoscopy · 2016Pooled it
- Single-incision laparoscopic surgery through the umbilicus is associated with a higher incidence of trocar-site hernia than conventional laparoscopy: a meta-analysis of randomized controlled trials.Hernia : the journal of hernias and abdominal wall surgery · 2016Pooled it
- Single-incision laparoscopic cholecystectomy: a systematic review of methodology and outcomes.Surgery today · 2015Pooled it
- Fewer-than-four ports versus four ports for laparoscopic cholecystectomy.The Cochrane database of systematic reviews · 2014Pooled it
- Systematic review with meta-analysis of prospective randomized trials comparing minimally invasive video-assisted thyroidectomy (MIVAT) and conventional thyroidectomy (CT).Langenbeck's archives of surgery · 2013Pooled it
- Single incision versus conventional laparoscopic cholecystectomy outcomes: a meta-analysis of randomized controlled trials.PloS one · 2013Pooled it
- 3D laparoscopy does not reduce operative duration or errors in day-case laparoscopic cholecystectomy: a randomised controlled trial.Surgical endoscopy · 2020Trial
- Is 3D faster and safer than 4K laparoscopic cholecystectomy? A randomised-controlled trial.Surgical endoscopy · 2020Trial
- Short-term outcomes of single-site robotic cholecystectomy versus four-port laparoscopic cholecystectomy: a prospective, randomized, double-blind trial.Surgical endoscopy · 2016Trial
- Impact of single-incision laparoscopic cholecystectomy (SILC) versus conventional laparoscopic cholecystectomy (CLC) procedures on surgeon stress and workload: a randomized controlled trial.Surgical endoscopy · 2016Trial
- A randomized controlled trial comparing post-operative pain in single-incision laparoscopic cholecystectomy versus conventional laparoscopic cholecystectomy.World journal of surgery · 2015Trial
- Potential benefits of single-port compared to multiport laparoscopic inguinal herniorraphy: a prospective randomized controlled study.Hernia : the journal of hernias and abdominal wall surgery · 2014Trial
- Safety and feasibility of robotic single-port (SP) cholecystectomy compared to conventional laparoscopic cholecystectomy: a propensity score matching analysis.Surgical endoscopy · 2026Article
- Single-Port Laparoscopy Compared with Conventional Laparoscopic Surgery: A Systematic Review and Meta-Analysis.Journal of clinical medicine · 2025Review
- Our initial single port robotic cholecystectomy experience: A feasible and safe option for benign gallbladder diseases.World journal of gastrointestinal endoscopy · 2022Article
- Laparoscopic gastrojejunostomy with laparoscopic-assisted percutaneous endoscopic gastrostomy for superior mesenteric artery syndrome with dysphagia: a case report.Surgical case reports · 2022Article
Corrections and comments
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Authors and funding
4 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundSingle-incision laparoscopic cholecystectomy (SILC) has gained acceptance among surgeons as there is a trend to minimize the invasiveness of laparoscopy. The aim of this meta-analysis has been to assess the feasibility and safety of SILC when compared to conventional multiport laparoscopic cholecystectomy (CMLC).
methodsA literature search for trials comparing SILC and CMLC was performed. Studies were reviewed for the outcomes of interest: patient characteristics; operative time and conversion rate; postoperative pain; length of hospital stay; postoperative complications; and patient satisfactory score (0-10). Standardized mean difference (SMD) was calculated for continuous variables and odds ratio for qualitative variables.
resultsTwelve prospective randomized trials comparing SILC and CMLC were analyzed. Overall, 892 patients were randomized to either SILC (465) or CMLC (427). Operative time was significantly longer in SILC (63.0 vs. 45.8 min, SMD = 1.004, 95% CI = 0.434-1.573). Patient satisfactory score significantly favored SILC (8.2 vs. 7.2, SMD = -0.759, 95% CI = -1.064 to -0.455). No other difference was found.
conclusionsSILC is a safe and effective procedure for the treatment of uncomplicated benign gallbladder disease with a significant patient satisfaction. New multicenter randomized trials are expected to evaluate SILC in more complex circumstances such as acute cholecystitis, previous abdominal surgery, and severe obesity.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.