ArticleAnnals of surgical oncology2012
Cognitive and psychological impact of BRCA genetic counseling in before and after definitive surgery breast cancer patients.
Article in Annals of surgical oncology, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers, 2 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
18 citing papers in PubMed, 2 syntheses or guidelines pooled it.
- Evidence-based advancements in breast cancer genetic counseling: a review.Breast cancer (Tokyo, Japan) · 2025Pooled it
- A Rapid Systematic Review of Outcomes Studies in Genetic Counseling.Journal of genetic counseling · 2017Pooled it
- Does rapid genetic counseling and testing in newly diagnosed breast cancer patients cause additional psychosocial distress? results from a randomized clinical trial.Genetics in medicine : official journal of the American College of Medical Genetics · 2016Trial
- Oncological Genetic Counseling in Hereditary Breast and Ovarian Cancers and Lynch Syndrome High-Risk Subjects: Evaluation of Efficacy and Outcomes Using the Genomics Outcome Scale.Human mutation · 2026Article
- Psychosocial impact of proactive rapid genetic counseling following breast cancer diagnosis.Psycho-oncology · 2022Article
- Physician Communication and Patient Understanding of Molecular Testing Terminology.The oncologist · 2021Article
- Integrating stakeholder feedback in translational genomics research: an ethnographic analysis of a study protocol's evolution.Genetics in medicine : official journal of the American College of Medical Genetics · 2020Article
- Communication about genetic testing with breast and ovarian cancer patients: a scoping review.European journal of human genetics : EJHG · 2019Article
- The importance of genetic counselling in genome-wide sequencing.Nature reviews. Genetics · 2018Review
- Risk Perception and Psychological Distress in Genetic Counselling for Hereditary Breast and/or Ovarian Cancer.Journal of genetic counseling · 2017Article
- Improving Access to Cancer Genetic Counseling through Telegenetics - A Bayhealth - University of Pennsylvania Initiative.Delaware journal of public health · 2017Article
- Article
- Evaluation of a pharmacogenetic educational toolkit for community pharmacists.Pharmacogenomics · 2016Article
- BRCA1/2 testing in newly diagnosed breast and ovarian cancer patients without prior genetic counselling: the DNA-BONus study.European journal of human genetics : EJHG · 2016Article
- Population-Based BRCA1/2 Testing in Ashkenazi Jews: Ready for Prime Time.Journal of the National Comprehensive Cancer Network : JNCCN · 2016Article
- Breast Cancer Genetic Counseling: A Surgeon's Perspective.Frontiers in surgery · 2016Review
- Breast Cancer Survivors' Knowledge of Hereditary Breast and Ovarian Cancer following Genetic Counseling: An Exploration of General and Survivor-Specific Knowledge Items.Public health genomics · 2016Article
- A Case for Inclusion of Genetic Counselors in Cardiac Care.Cardiology in reviewReview
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
9 authors.
Funding
Abstract
purposeTo examine changes in cancer-related knowledge, distress, and decisional conflict from pre- to post-genetic counseling (GC) in before (BDS) and after (ADS) definitive surgery breast cancer (BC) patients.
methodsSociodemographic and clinical characteristics were collected at baseline; primary outcome data were collected before (T1) and after (T2) pretest GC. Within group changes for cancer-related knowledge, distress, and decisional conflict over genetic testing were compared by Wilcoxon signed-rank tests.
resultsOf 103 BC patients, 87 were ADS and 16 were BDS. Analyses revealed that both groups reported significant increases in knowledge between T1 and T2 (median change 4.2, p = 0.004, and 2.7, p < 0.001, for BDS and ADS patients, respectively). Overall cancer-related distress showed a downward trend between T1 and T2 for both groups and was significant for BDS patients (p = 0.041). Reports of BDS patients trended toward overall and subscale-specific increases in decisional conflict, with the exception of the uncertainty which trended downward, but did not reach significance. Overall decisional conflict decreased in ADS patients, approaching marginal significance (p = 0.056), with significant improvements in informed decision making (median change -12.6, p < 0.001; i.e., pretest GC yielded improved knowledge of benefits, risks, and side effects of available options).
conclusionsThese pilot data suggest that pretest GC increases cancer-related knowledge for both BDS and ADS patients, decreases distress in BDS patients, and improves informed decision making in ADS patients. Future studies with larger sample sizes are needed to replicate these results.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.