ArticleNeuroradiology2012
Detection and treatment of spinal CSF leaks in idiopathic intracranial hypotension.
Article in Neuroradiology, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers, 1 of them a synthesis that pooled it.
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Who cites it
11 citing papers in PubMed, 1 synthesis or guideline pooled it, 47 citations in OpenAlex.
- The status of diagnosis and treatment to intracranial hypotension, including SIH.The journal of headache and pain · 2017Pooled it
- Trial
- Intracranial hypotension associated with shoulder injury: a case report.Anaesthesiology intensive therapy · 2025Article
- Neurotoxicity from intrathecal gadolinium administration: Case presentation and brief review.Neurology. Clinical practice · 2020Article
- Spinal Cerebrospinal Fluid Leakage in Spontaneous Intracranial Hypotension: An Intrathecal Gadolinium Enhanced MR-Myelography Study.Journal of the Belgian Society of Radiology · 2020Article
- MRI myelography for diagnosis and targeted blood patching of multilevel thoracic spine CSF leaks: Report of 2 cases.Radiology case reports · 2019Article
- [Cerebrospinal fluid leakage. Indications, technique and results of treatment with a blood patch].Der Radiologe · 2015Article
- MR myelography for identification of spinal CSF leak in spontaneous intracranial hypotension.AJNR. American journal of neuroradiology · 2014Article
- Apparent diffusion coefficient measurements to support a diagnosis of intracranial hypotension.The British journal of radiology · 2014Article
- A new mechanism of cerebrospinal fluid leakage after lumboperitoneal shunt: a theory of shunt side hole--case report.Neurologia medico-chirurgica · 2014Article
- Intracranial hypotension after trauma.SpringerPlus · 2014Article
Corrections and comments
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Authors and funding
6 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
introductionThis study aimed to evaluate the diagnostic imaging findings and treatment results of patients with idiopathic intracranial hypotension (IIH) due to cerebrospinal fluid (CSF) leaks.
methodsBetween February 2009 and April 2012, 26 IIH patients (15 men, median age 49 years) presenting with orthostatic headache (n = 20) and/or with spontaneous subdural effusions or subarachnoid hemorrhage (n = 19) were enrolled. Twenty-three patients underwent a whole spine CT and MRI myelography, starting 45 min after the intrathecal injection of 9 cc of iomeprol (Imeron 300 M) and 1 cc of gadobutrolum (Gadovist). Three patients only underwent MR myelography after intrathecal gadobutrolum injection. Adjacent to the level(s) of the detected CSF leak(s) along the nerve roots, 20 cc of fresh venous blood with 0.5 cc Gadovist was injected epidurally (blood patch, BP). The distribution of the BP was visualized by MRI the following day. Treatment results were evaluated clinically and by myelography 2 weeks after the application of the BP. Retreatment was offered to patients with persistent symptoms and continued CSF leakage.
resultsCSF leaks were detected at the cervical (n = 12), thoracic (n = 25), or lumbar (n = 21) spine. In 23 patients, more than one spinal segment was affected. One patient refused treatment. BP were applied in one (n = 9) or several (n = 16) levels. Clinical and/or radiological improvement was achieved after one (n = 16), two (n = 5), three (n = 3), or five (n = 1) BPs.
conclusionCT and MRI myelography allow the reliable detection of spinal CSF leaks. The targeted and eventually repeated epidural BP procedure is a safe and efficacious treatment.
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