ArticleOrganic letters2012
Palladium-catalyzed N-monoarylation of amidines and a one-pot synthesis of quinazoline derivatives.
Article in Organic letters, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.
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Who cites it
14 citing papers in PubMed.
- Recent trends of organic synthesis through cobalt metal-based catalysis: a review.RSC advances · 2026Review
- Unlocking Catalyst Activation as a Critical Bottleneck in Cross-Coupling Reactions: Room-Temperature Couplings of Weak Nucleophiles Enabled by [Pd(1-MeNAP)TFA]Angewandte Chemie (International ed. in English) · 2026Article
- Article
- Recent Advances in Metal-Catalyzed Approaches for the Synthesis of Quinazoline Derivatives.Molecules (Basel, Switzerland) · 2024Review
- Applications of palladium-catalyzed C-N cross-coupling reactions in pharmaceutical compounds.RSC advances · 2023Review
- Cu(ii)-catalyzed C-N coupling of 2-aminobenzothiazoles with boronic acids at room temperature.RSC advances · 2023Article
- Article
- Catalyst-free one-pot, four-component approach for the synthesis of di- and tri-substitutedRSC advances · 2021Article
- Efficient Copper-Catalyzed Multicomponent Synthesis ofJournal of the American Chemical Society · 2019Article
- Direct synthesis of 2-oxo-acetamidines from methyl ketones, aromatic amines and DMFRSC advances · 2019Article
- Applications of Palladium-Catalyzed C-N Cross-Coupling Reactions.Chemical reviews · 2016Review
- Decarboxylative palladium(II)-catalyzed synthesis of aryl amidines from aryl carboxylic acids: development and mechanistic investigation.Chemistry (Weinheim an der Bergstrasse, Germany) · 2013Article
- Quinazoline derivatives: synthesis and bioactivities.Chemistry Central journal · 2013Article
- Investigating the dearomative rearrangement of biaryl phosphine-ligated Pd(II) complexes.Journal of the American Chemical Society · 2012Article
Corrections and comments
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Authors and funding
3 authors.
Funding
Abstract
A method for the Pd-catalyzed N-arylation of both aryl and alkyl amidines with a wide range of aryl bromides, chlorides, and triflates is described. The reactions proceed in short reaction times and with excellent selectivity for monoarylation. A one-pot synthesis of quinazoline derivatives, via addition of an aldehyde to the crude reaction mixture following Pd-catalyzed N-arylation, is also demonstrated.
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Registered trials
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