ArticleThe American journal of tropical medicine and hygiene2012
A prospective assessment of the accuracy of commercial IgM ELISAs in diagnosis of Japanese encephalitis virus infections in patients with suspected central nervous system infections in Laos.
Article in The American journal of tropical medicine and hygiene, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers, 1 of them a synthesis that pooled it.
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Who cites it
14 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Pooled it
- Detection of central nervous system viral infections in adults in Manado, North Sulawesi, Indonesia.PloS one · 2018Trial
- Rapid Differential Detection of Japanese Encephalitis Virus and Getah Virus in Pigs or Mosquitos by a Duplex TaqMan Real-Time RT-PCR Assay.Frontiers in veterinary science · 2022Article
- The current burden of Japanese encephalitis and the estimated impacts of vaccination: Combining estimates of the spatial distribution and transmission intensity of a zoonotic pathogen.PLoS neglected tropical diseases · 2021Article
- Management of Central Nervous System Infections, Vientiane, Laos, 2003-2011.Emerging infectious diseases · 2019Article
- Poor performance of two rapid immunochromatographic assays for anti-Japanese encephalitis virus immunoglobulin M detection in cerebrospinal fluid and serum from patients with suspected Japanese encephalitis virus infection in Laos.Transactions of the Royal Society of Tropical Medicine and Hygiene · 2017Article
- Epidemiologic Survey of Japanese Encephalitis Virus Infection, Tibet, China, 2015.Emerging infectious diseases · 2017Article
- Pre-cut Filter Paper for Detecting Anti-Japanese Encephalitis Virus IgM from Dried Cerebrospinal Fluid Spots.PLoS neglected tropical diseases · 2016Article
- Blood-Brain Barrier Function and Biomarkers of Central Nervous System Injury in Rickettsial Versus Other Neurological Infections in Laos.The American journal of tropical medicine and hygiene · 2015Article
- Cultural drivers and health-seeking behaviours that impact on the transmission of pig-associated zoonoses in Lao People's Democratic Republic.Infectious diseases of poverty · 2015Article
- Epidemiology of Japanese encephalitis: past, present, and future prospects.Therapeutics and clinical risk management · 2015Review
- Epidemiological study of Japanese encephalitis virus in Vientiane, Lao PDR, in 1990s.TheScientificWorldJournal · 2015Article
- Causes of non-malarial fever in Laos: a prospective study.The Lancet. Global health · 2013Article
- An epidemic of dengue-1 in a remote village in rural Laos.PLoS neglected tropical diseases · 2013Article
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Authors and funding
10 authors.
Funding
Abstract
Japanese encephalitis virus (JEV) is a major cause of encephalitis in Asia. We estimated the diagnostic accuracy of two anti-JEV immunoglobulin M (IgM) enzyme-linked immunosorbent assays (ELISAs) (Panbio and XCyton JEVCheX) compared with a reference standard (AFRIMS JEV MAC ELISA) in a prospective study of the causes of central nervous system infections in Laos. Cerebrospinal fluid (CSF; 515 patients) and serum samples (182 patients) from those admitted to Mahosot Hospital, Vientiane, were tested. The CSF from 14.5% of acute encephalitis syndrome (AES) patients and 10.1% from those with AES and meningitis were positive for anti-JEV IgM in the reference ELISA. The sensitivities for CSF were 65.4% (95% confidence interval [CI] = 51-78) (Xcyton), 69.2% (95% CI = 55-81) (Panbio), however 96.2% (95% CI = 87-100) with Panbio Ravi criteria. Specificities were 89-100%. For admission sera from AES patients, sensitivities and specificities of the Panbio ELISA were 85.7% (95% CI = 42-100%) and 92.9% (95% CI = 83-98%), respectively.
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