ArticleThe Journal of neuroscience : the official journal of the Society for Neuroscience2012
Active engagement improves primary auditory cortical neurons' ability to discriminate temporal modulation.
Article in The Journal of neuroscience : the official journal of the Society for Neuroscience, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 71 papers.
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Who cites it
71 citing papers in PubMed.
- Noise-induced hearing loss delays auditory learning and reduces the influence of acoustic evidence on choice.bioRxiv : the preprint server for biology · 2026Article
- A cortical output channel for perceptual categorization.Science advances · 2026Article
- Neural competition between prefrontal and auditory cortex constrains novel sound strategy learning.Science advances · 2026Article
- Temporal integration in the subcortical auditory system and behavioral evidence of its dysfunction after "temporary" noise-induced hearing loss.bioRxiv : the preprint server for biology · 2026Article
- Behavioral engagement facilitates auditory neuron responses beyond their receptive fields.PLoS biology · 2026Article
- Modulation of Auditory Cortex Activity in Salicylate-Induced Tinnitus Rats via Deep Brain Stimulation of the Inferior Colliculus.Brain and behavior · 2025Article
- Neural Correlates of Perceptual Plasticity in the Auditory Midbrain and Thalamus.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2025Article
- Hierarchical emergence of opponent coding in auditory belt cortex.Journal of neurophysiology · 2025Article
- A spatial code for temporal information is necessary for efficient sensory learning.Science advances · 2025Article
- Hierarchical differences in the encoding of amplitude modulation in the subcortical auditory system of awake nonhuman primates.Journal of neurophysiology · 2024Article
- Article
- Orbitofrontal cortex modulates auditory cortical sensitivity and sound perception in Mongolian gerbils.Current biology : CB · 2024Article
- Neural correlates of flexible sound perception in the auditory midbrain and thalamus.bioRxiv : the preprint server for biology · 2024Article
- Intracranial Mapping of Response Latencies and Task Effects for Spoken Syllable Processing in the Human Brain.bioRxiv : the preprint server for biology · 2024Article
- Changes in neural readout of response magnitude during auditory streaming do not correlate with behavioral choice in the auditory cortex.Cell reports · 2023Article
- Dynamics and maintenance of categorical responses in primary auditory cortex during task engagement.eLife · 2023Article
- Organization of orbitofrontal-auditory pathways in the Mongolian gerbil.The Journal of comparative neurology · 2023Article
- Dynamics of cortical contrast adaptation predict perception of signals in noise.Nature communications · 2023Article
- Sleep-like changes in neural processing emerge during sleep deprivation in early auditory cortex.Current biology : CB · 2023Article
- Adaptation in auditory processing.Physiological reviews · 2023Review
11 more citing papers are in PubMed but not listed here.
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4 authors.
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Abstract
The effect of attention on single neuron responses in the auditory system is unresolved. We found that when monkeys discriminated temporally amplitude modulated (AM) from unmodulated sounds, primary auditory cortical (A1) neurons better discriminated those sounds than when the monkeys were not discriminating them. This was observed for both average firing rate and vector strength (VS), a measure of how well neurons temporally follow the stimulus' temporal modulation. When data were separated by nonsynchronized and synchronized responses, the firing rate of nonsynchronized responses best distinguished AM- noise from unmodulated noise, followed by VS for synchronized responses, with firing rate for synchronized neurons providing the poorest AM discrimination. Firing rate-based AM discrimination for synchronized neurons, however, improved most with task engagement, showing that the least sensitive code in the passive condition improves the most with task engagement. Rate coding improved due to larger increases in absolute firing rate at higher modulation depths than for lower depths and unmodulated sounds. Relative to spontaneous activity (which increased with engagement), the response to unmodulated sounds decreased substantially. The temporal coding improvement--responses more precisely temporally following a stimulus when animals were required to attend to it--expands the framework of possible mechanisms of attention to include increasing temporal precision of stimulus following. These findings provide a crucial step to understanding the coding of temporal modulation and support a model in which rate and temporal coding work in parallel, permitting a multiplexed code for temporal modulation, and for a complementary representation of rate and temporal coding.
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