ArticleThe Journal of neuroscience : the official journal of the Society for Neuroscience2012
Robustness of cortical topography across fields, laminae, anesthetic states, and neurophysiological signal types.
Article in The Journal of neuroscience : the official journal of the Society for Neuroscience, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 136 papers.
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Who cites it
136 citing papers in PubMed.
- Immersive audiomotor game play enhances neural and perceptual salience of weak signals in noise.Proceedings of the National Academy of Sciences of the United States of America · 2014Trial
- Trends in neuroprosthetic technologies to restore sensations.Biomedical engineering letters · 2026Review
- Altered folate metabolism disrupts auditory function from neonatal vocalizations to adult perceptual precision.Journal of neurodevelopmental disorders · 2026Article
- Layer 6 is a hub for cholinergic modulation in the mouse auditory cortex.Cerebral cortex (New York, N.Y. : 1991) · 2026Article
- Differential Myeloarchitecture of Subfields of the Mammalian Auditory Cortex: A Comparative Approach.Brain, behavior and evolution · 2026Review
- Orthogonal spectral and temporal envelope representation during the onset phase in auditory cortex.iScience · 2025Article
- Article
- A Rapid Anterior Auditory Processing Stream through the Insulo-parietal Auditory Field in the Rat.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2025Article
- Patchy harmonic functional connectivity of the mouse auditory cortex.Proceedings of the National Academy of Sciences of the United States of America · 2025Article
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- Noncanonical short-latency auditory pathway directly activates deep cortical layers.Nature communications · 2025Article
- Layer 6 is a hub for cholinergic modulation in the mouse auditory cortex.bioRxiv : the preprint server for biology · 2025Article
- Spatially clustered neurons in the bat midbrain encode vocalization categories.Nature neuroscience · 2025Article
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- Segregated input to thalamic areas that project differently to core and shell auditory cortical fields.iScience · 2025Article
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- Hemispheric Asymmetry of Intracortical Myelin Orientation in the Mouse Auditory Cortex.The European journal of neuroscience · 2025Article
- Anatomical pathways and functional implications of the rodent auditory system-basal ganglia interconnectivity.Frontiers in behavioral neuroscience · 2025Review
- Receptive-field nonlinearities in primary auditory cortex: a comparative perspective.Cerebral cortex (New York, N.Y. : 1991) · 2024Article
- Sensation and expectation are embedded in mouse motor cortical activity.Cell reports · 2024Article
76 more citing papers are in PubMed but not listed here.
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6 authors.
Funding
Abstract
Topographically organized maps of the sensory receptor epithelia are regarded as cornerstones of cortical organization as well as valuable readouts of diverse biological processes ranging from evolution to neural plasticity. However, maps are most often derived from multiunit activity recorded in the thalamic input layers of anesthetized animals using near-threshold stimuli. Less distinct topography has been described by studies that deviated from the formula above, which brings into question the generality of the principle. Here, we explicitly compared the strength of tonotopic organization at various depths within core and belt regions of the auditory cortex using electrophysiological measurements ranging from single units to delta-band local field potentials (LFP) in the awake and anesthetized mouse. Unit recordings in the middle cortical layers revealed a precise tonotopic organization in core, but not belt, regions of auditory cortex that was similarly robust in awake and anesthetized conditions. In core fields, tonotopy was degraded outside the middle layers or when LFP signals were substituted for unit activity, due to an increasing proportion of recording sites with irregular tuning for pure tones. However, restricting our analysis to clearly defined receptive fields revealed an equivalent tonotopic organization in all layers of the cortical column and for LFP activity ranging from gamma to theta bands. Thus, core fields represent a transition between topographically organized simple receptive field arrangements that extend throughout all layers of the cortical column and the emergence of nontonotopic representations outside the input layers that are further elaborated in the belt fields.
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