Trial reportVeterinary journal (London, England : 1997)2012
Acute phase response to Mycoplasma haemofelis and 'Candidatus Mycoplasma haemominutum' infection in FIV-infected and non-FIV-infected cats.
Trial report in Veterinary journal (London, England : 1997), 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
15 citing papers in PubMed, 33 citations in OpenAlex.
- Investigation of Some Clinicopathologic Alterations in Cats Infected With Mycoplasma haemofelis and Candidatus Mycoplasma haemominutum in Mashhad, Iran: An Observational Cross-Sectional Study.Veterinary medicine and science · 2026Article
- Evaluation of multiple methods for the diagnosis of equine Hemomycoplasmosis in Misan, Iraq.Open veterinary journal · 2026Article
- Further Insights into The Pathogenic Mechanisms of HaemotropicTropical life sciences research · 2024Article
- Acute phase proteins and total antioxidant capacity in free-roaming cats infected by pathogenic leptospires.BMC veterinary research · 2023Article
- Cat alpha-1-acid glycoprotein enzyme-linked immunosorbent assay: performance characteristics and reference intervals.Journal of feline medicine and surgery · 2023Article
- Article
- Analytical Validation of Two Point-of-Care Assays for Serum Amyloid A Measurements in Cats.Animals : an open access journal from MDPI · 2021Article
- Review of clinical aspects, epidemiology and diagnosis of haemotropic Mycoplasma ovis in small ruminants: current status and future perspectives in tropics focusing on Malaysia.Tropical animal health and production · 2020Review
- A Clinical Investigation on Serum Amyloid A Concentration in Client-Owned Healthy and Diseased Cats in a Primary Care Animal Hospital.Veterinary sciences · 2020Article
- Concomitant feline immunodeficiency virus (FIV) andThe Canadian veterinary journal = La revue veterinaire canadienne · 2018Article
- Serum acute phase proteins in Dirofilaria immitis and Wolbachia seropositive cats.Journal of feline medicine and surgery · 2017Article
- Monitoring acute phase proteins in retrovirus infected cats undergoing feline interferon-ω therapy.The Journal of small animal practice · 2014Article
- Prevalence and risk factor analysis of feline haemoplasma infection in New Zealand domestic cats using a real-time PCR assay.Journal of feline medicine and surgery · 2013Article
- Rapid detection of haemotropic mycoplasma infection of feline erythrocytes using a novel flow cytometric approach.Parasites & vectors · 2013Article
- Amyloidosis in association with spontaneous feline immunodeficiency virus infection.Journal of feline medicine and surgery · 2013Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors at 3 institutions in 2 countries.
Funding
Abstract
The pathogenicity of Haemoplasma spp. in cats varies with 'Candidatus Mycoplasma haemominutum' (CMhm) causing subclinical infection while Mycoplasma haemofelis (Mhf) often induces haemolytic anaemia. The aims of this study were to characterise the acute phase response (APR) of the cat to experimental infection with Mhf or CMhm, and to determine whether chronic feline immunodeficiency virus (FIV) infection influences this response. The acute phase proteins serum amyloid A (SAA), haptoglobin (Hp) and α-1-acid glycoprotein (AGP) concentrations were measured pre-infection and every 7-14 days up to day 100 post-infection (pi) in cats infected with either Mhf or CMhm. Half of each group of cats (6/12) were chronically and subclinically infected with FIV. Marbofloxacin treatment was given on days 16-44 pi to half of the Mhf-infected cats, and on days 49-77 pi to half of the CMhm-infected cats. FIV-infected animals had significantly lower AGP concentrations, and significantly greater Hp concentrations than non-FIV-infected cats when infected with CMhm and Mhf, respectively. Both CMhm and Mhf infection were associated with significant increases in SAA concentrations, while AGP concentrations were only significantly increased by Mhf infection. Mhf-infected cats had significantly greater SAA concentrations than CMhm-infected animals. Both Mhf and CMhm infections were associated with an APR, with Mhf infection inducing a greater response. Chronic FIV infection appeared to modify the APR, which varied with the infecting Haemoplasma species.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.