ArticlePloS one2012
The course of habituation of the proboscis extension reflex can be predicted by sucrose responsiveness in Drosophila.
Article in PloS one, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.
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Who cites it
8 citing papers in PubMed.
- AmelOBP4: an antenna-specific odor-binding protein gene required for olfactory behavior in the honey bee (Apis mellifera).Frontiers in zoology · 2025Article
- A Drosophila model relevant to chemotherapy-related cognitive impairment.Scientific reports · 2023Article
- Temporally specific engagement of distinct neuronal circuits regulating olfactory habituation ineLife · 2018Article
- A Fly's Eye View of Natural and Drug Reward.Frontiers in physiology · 2018Review
- Limitations of learning in the proboscis reflex of the flower visiting syrphid fly Eristalis tenax.PloS one · 2018Article
- Metabolic learning and memory formation by the brain influence systemic metabolic homeostasis.Nature communications · 2015Article
- Habituation, sensitization, and Pavlovian conditioning.Frontiers in integrative neuroscience · 2014Article
- Apis mellifera octopamine receptor 1 (AmOA1) expression in antennal lobe networks of the honey bee (Apis mellifera) and fruit fly (Drosophila melanogaster).Frontiers in systems neuroscience · 2013Article
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Authors and funding
2 authors.
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Abstract
The proboscis extension reflex (PER) is triggered when insects' gustatory receptors contact appetitive stimuli, so it provides a behavioral readout for perceptual encoding of tastants. Research on the experience dependent modulation of PER in Drosophila has been hindered by the difficulty of obtaining reliable measures of memory-driven change in PER probability in the background of larger changes induced by physiological state. In this study, we showed that the course of PER habituation can be predicted by the degree of sucrose responsiveness in Drosophila. We assessed early response parameters, including the number of proboscis extensions and labellar movements in the first five trials, the trial to start responding, and the trial to make the first stop to quantify responsiveness, which predicted the upcoming pattern of both the short-term and 1 hour memory of PER habituation for individual flies. The cAMP signaling pathway mutant rutabaga displayed deficits in attunement of perceptual salience of sucrose to physiological demands and stimulus-driven sensitization.
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