ArticlePloS one2012
Characterization of the rainbow trout egg microRNA transcriptome.
Article in PloS one, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 30 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
30 citing papers in PubMed, 78 citations in OpenAlex.
- Potential Role of microRNAs in Response toArchives of Razi Institute · 2023Review
- Identification and Characterization of Sex-Biased miRNAs in the Golden Pompano (Animals : an open access journal from MDPI · 2022Article
- Characterization of miRNAs in Embryonic, Larval, and Adult Lumpfish Provides a Reference miRNAome forBiology · 2022Article
- Identification and Characterization of Osmoregulation Related MicroRNAs in Gills of Hybrid Tilapia Under Three Types of Osmotic Stress.Frontiers in genetics · 2021Article
- Potential immune regulatory role of miR-146a upon Aeromonas hydrophila and Edwardsiella piscicida infections in zebrafish.Brazilian journal of microbiology : [publication of the Brazilian Society for Microbiology] · 2020Article
- Identification and Comparison of microRNAs in the Gonad of the Yellowfin Seabream (International journal of molecular sciences · 2020Article
- miRNAs and Novel Food Compounds Related to the Browning Process.International journal of molecular sciences · 2019Review
- Induced androgenetic development in rainbow trout and transcriptome analysis of irradiated eggs.Scientific reports · 2019Article
- Postovulatory maternal transcriptome in Atlantic salmon and its relation to developmental potential of embryos.BMC genomics · 2019Article
- Identification of Novel MicroRNAs and Characterization of MicroRNA Expression Profiles in Zebrafish Ovarian Follicular Cells.Frontiers in endocrinology · 2019Article
- A myriad of roles of miR-25 in health and disease.Oncotarget · 2018Review
- Identification of dysregulated modules based on network entropy in type 1 diabetes.Experimental and therapeutic medicine · 2018Article
- Circulating miRNA measurements are reflective of cholesterol-based changes in rainbow trout (Oncorhynchus mykiss).PloS one · 2018Article
- miR-30 Family: A Promising Regulator in Development and Disease.BioMed research international · 2018Review
- Epigenetic considerations in aquaculture.PeerJ · 2017Article
- Article
- Identification of Mitochondrial Genome-Encoded Small RNAs Related to Egg Deterioration Caused by Postovulatory Aging in Rainbow Trout.Marine biotechnology (New York, N.Y.) · 2016Article
- Integrated analysis of miRNA and mRNA expression profiles in tilapia gonads at an early stage of sex differentiation.BMC genomics · 2016Article
- Identification and Functional Prediction of Large Intergenic Noncoding RNAs (lincRNAs) in Rainbow Trout (Oncorhynchus mykiss).Marine biotechnology (New York, N.Y.) · 2016Article
- Characterization of an extensive rainbow trout miRNA transcriptome by next generation sequencing.BMC genomics · 2016Article
Corrections and comments
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Authors and funding
5 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
MicroRNAs (miRNAs) are a class of endogenous small non-coding RNA molecules that regulate post-transcriptional expression of target genes and play important roles in animal development. The objectives of this study were to characterize the egg miRNA transcriptome and identify novel egg-predominant miRNAs in rainbow trout. Small RNAs isolated from mature unfertilized rainbow trout eggs were subjected to deep sequencing using an Illumina Genome Analyzer. The massive sequencing produced 24,621,741 quality reads, among which, 266 known miRNAs were identified and 230 putatively novel miRNAs were predicted. The most abundantly known miRNAs are let-7 and miR-21, accounting for 24.06% and 18.71% of the known miRNAs, respectively. Other known miRNAs which are abundantly present in eggs include miR-24, miR-202, miR-148, miR-30, miR-10, miR-146, miR-25, and miR-143. Real time PCR analysis using cDNAs derived from 10 tissues validated 87 out of 90 selected putative miRNAs and identified three novel miRNAs predominantly expressed in rainbow trout eggs. Each of these novel egg-predominant miRNAs is predicted to target a significant number of genes, most of which are significantly down-regulated in naturally ovulated rainbow trout eggs based on analysis of publicly available microarray data sets. Quantitative real time PCR analysis also demonstrated low expression of a selected number of target genes in eggs relative to liver and muscle tissues. This study represents the first complete survey of miRNAs in fish eggs and provides a starting point for future studies aimed at understanding the roles of miRNAs in controlling egg quality and early embryogenesis in rainbow trout.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.