ArticlePloS one2012
High resolution analysis of meiotic chromosome structure and behaviour in barley (Hordeum vulgare L.).
Article in PloS one, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 37 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
37 citing papers in PubMed, 62 citations in OpenAlex.
- Sex chromosome pairing and multivalent associations during meiosis in diploid and polyploid Silene latifolia.Plant physiology · 2026Article
- Loss of E3 ligase HvST1 function substantially increases distal crossover frequency.The New phytologist · 2026Article
- Impact of soil and climate on barley (Hordeum vulgare L.) salinity tolerance in diverse arid and saline conditions.Scientific reports · 2025Article
- Non-Canonical Male Meiosis in a Marine Gastropod,Biology · 2025Article
- Cytological analysis of the diploid-like inheritance of newly synthesized allotetraploid wheat.Chromosome research : an international journal on the molecular, supramolecular and evolutionary aspects of chromosome biology · 2023Article
- The Control of the Crossover Localization in Allium.International journal of molecular sciences · 2023Article
- Crossover patterning in plants.Plant reproduction · 2023Review
- Bouquet Formation Failure in Meiosis of FPlants (Basel, Switzerland) · 2022Article
- ZYP1 is required for obligate cross-over formation and cross-over interference inProceedings of the National Academy of Sciences of the United States of America · 2021Article
- Chromosome-nuclear envelope tethering - a process that orchestrates homologue pairing during plant meiosis?Journal of cell science · 2020Review
- Dynamic localization of SPO11-1 and conformational changes of meiotic axial elements during recombination initiation of maize meiosis.PLoS genetics · 2020Article
- The Cohesin Complex Subunit ZmSMC3 Participates in Meiotic Centromere Pairing in Maize.The Plant cell · 2020Article
- Probing the 3D architecture of the plant nucleus with microscopy approaches: challenges and solutions.Nucleus (Austin, Tex.) · 2019Review
- Variation in Recombination Rate Is Shaped by Domestication and Environmental Conditions in Barley.Molecular biology and evolution · 2019Article
- desynaptic5 carries a spontaneous semi-dominant mutation affecting Disrupted Meiotic cDNA 1 in barley.Journal of experimental botany · 2019Article
- Ultrastructure and Dynamics of Synaptonemal Complex Components During Meiotic Pairing and Synapsis of Standard (A) and Accessory (B) Rye Chromosomes.Frontiers in plant science · 2019Article
- The telomere bouquet is a hub where meiotic double-strand breaks, synapsis, and stable homolog juxtaposition are coordinated in the zebrafish, Danio rerio.PLoS genetics · 2019Article
- B chromosomes are associated with redistribution of genetic recombination towards lower recombination chromosomal regions in perennial ryegrass.Journal of experimental botany · 2018Article
- Not just gene expression: 3D implications of chromatin modifications during sexual plant reproduction.Plant cell reports · 2018Review
- Superresolution expansion microscopy reveals the three-dimensional organization of theProceedings of the National Academy of Sciences of the United States of America · 2017Article
Corrections and comments
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Authors and funding
4 authors at 2 institutions in 1 country.
Funding
Abstract
Reciprocal crossing over and independent assortment of chromosomes during meiosis generate most of the genetic variation in sexually reproducing organisms. In barley, crossovers are confined primarily to distal regions of the chromosomes, which means that a substantial proportion of the genes of this crop rarely, if ever, engage in recombination events. There is potentially much to be gained by redistributing crossovers to more proximal regions, but our ability to achieve this is dependent upon a far better understanding of meiosis in this species. This study explores the meiotic process by describing with unprecedented resolution the early behaviour of chromosomal domains, the progression of synapsis and the structure of the synaptonemal complex (SC). Using a combination of molecular cytogenetics and advanced fluorescence imaging, we show for the first time in this species that non-homologous centromeres are coupled prior to synapsis. We demonstrate that at early meiotic prophase the loading of the SC-associated structural protein ASY1, the cluster of telomeres, and distal synaptic initiation sites occupy the same polarised region of the nucleus. Through the use of advanced 3D image analysis, we show that synapsis is driven predominantly from the telomeres, and that new synaptic initiation sites arise during zygotene. In addition, we identified two different SC configurations through the use of super-resolution 3D structured illumination microscopy (3D-SIM).
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.