ArticlePloS one2012
Influence of age, circadian and homeostatic processes on inhibitory motor control: a Go/Nogo task study.
Article in PloS one, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 31 papers.
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Who cites it
31 citing papers in PubMed, 70 citations in OpenAlex.
- Trial
- Feedback Blunting: Total Sleep Deprivation Impairs Decision Making that Requires Updating Based on Feedback.Sleep · 2015Trial
- Evaluating Electroencephalogram-Based Predictive Model for Drowsiness Measurement to Reduce Accident Risk in Active Individuals: Protocol for a Preliminary Monocentric Study.JMIR research protocols · 2026Article
- Article
- Chronotype-specific associations of sleep-wake schedule with behavioral, physiological, and psychological parameters.Sleep advances : a journal of the Sleep Research Society · 2026Article
- Nightly variations in sleep quality and next-day cognitive performance: an in-home study in healthy older adults.Frontiers in aging neuroscience · 2026Article
- Variations of autonomic arousal mediate the reportability of mind blanking occurrences.Scientific reports · 2025Article
- Within- and between-individual associations between sleep and cognition in older community-dwelling individuals.Frontiers in aging · 2025Article
- Sleep/wake regularity influences how stress shapes executive function.Frontiers in sleep · 2024Article
- Article
- Cognitive control, bedtime patterns, and testing time in female adolescent students: behavioral and neuro-electrophysiological correlates.Frontiers in public health · 2023Article
- [Study on homeostasis and circadian rhythm of attention performance of different chronotypes in sleep deprivation].Sheng wu yi xue gong cheng xue za zhi = Journal of biomedical engineering = Shengwu yixue gongchengxue zazhi · 2022Article
- Strategies to Limit Cognitive Impairments under Sleep Restriction: Relationship to Stress Biomarkers.Brain sciences · 2022Article
- Sleep in Normal Aging, Homeostatic and Circadian Regulation and Vulnerability to Sleep Deprivation.Brain sciences · 2021Review
- Mood impairment is stronger in young than in older adults after sleep deprivation.Journal of sleep research · 2019Article
- Individual Differences in the Neural Basis of Response Inhibition After Sleep Deprivation Are Mediated by Chronotype.Frontiers in neurology · 2019Article
- Daytime Exposure to Blue-Enriched Light Counters the Effects of Sleep Restriction on Cortisol, Testosterone, Alpha-Amylase and Executive Processes.Frontiers in neuroscience · 2019Article
- Limited Benefit of Sleep Extension on Cognitive Deficits During Total Sleep Deprivation: Illustration With Two Executive Processes.Frontiers in neuroscience · 2019Article
- Are sluggish cognitive tempo symptoms associated with executive functioning in preschoolers?Child neuropsychology : a journal on normal and abnormal development in childhood and adolescence · 2018Article
- Ovarian hormones, sleep and cognition across the adult female lifespan: An integrated perspective.Frontiers in neuroendocrinology · 2017Review
Corrections and comments
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Authors and funding
8 authors at 6 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
introductionThe contribution of circadian system and sleep pressure influences on executive performance as a function of age has never been studied. The aim of our study was to determine the age-related evolution of inhibitory motor control (i.e., ability to suppress a prepotent motor response) and sustained attention under controlled high or low sleep pressure conditions.
methods14 healthy young males (mean age = 23 ± 2.7; 20-29 years) and 11 healthy older males (mean age = 68 ± 1.4; 66-70 years) were recruited. The volunteers were placed for 40 hours in "constant routine". In the "Sleep Deprivation SD" condition, the volunteer was kept awake for 40 hours to obtain a high sleep pressure condition interacting with the circadian process. In the "NAP" condition, the volunteer adopted a short wake/sleep cycle (150/75 min) resulting in a low sleep pressure condition to counteract the homeostatic pressure and investigate the circadian process. Performances were evaluated by a simple reaction time task and a Go/Nogo task repeated every 3H45.
resultsIn the SD condition, inhibitory motor control (i.e., ability to inhibit an inappropriate response) was impaired by extended wakefulness equally in both age groups (P<.01). Sustained attention (i.e. ability to respond accurately to appropriate stimuli) on the executive task decreased under sleep deprivation in both groups, and even more in young participants (P<.05). In the NAP condition, age did not influence the time course of inhibitory motor control or sustained attention. In the SD and NAP conditions, older participants had a less fluctuating reaction time performance across time of day than young participants (P<.001).
conclusionAging could be a protective factor against the effects of extended wakefulness especially on sustained attention failures due to an attenuation of sleep pressure with duration of time awake.
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