ArticlemBio2012
Ethanolamine: a signal to commence a host-associated lifestyle?
Article in mBio, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
15 citing papers in PubMed, 22 citations in OpenAlex.
- Article
- Pathogenesis and therapeutic strategies in the interaction between gut microbiota and enterohemorrhagic Escherichia coli infection.FEMS microbiology reviews · 2026Review
- Role of ethanolamine utilization and bacterial microcompartment formation inInfection and immunity · 2024Article
- Arm race among closely-related carbapenem-resistant Klebsiella pneumoniae clones.ISME communications · 2022Article
- Polyamine and Ethanolamine Metabolism in Bacteria as an Important Component of Nitrogen Assimilation for Survival and Pathogenicity.Medical sciences (Basel, Switzerland) · 2022Review
- Article
- Disease Tolerance inFrontiers in cellular and infection microbiology · 2019Review
- Article
- Ethanolamine is a valuable nutrient source that impacts Clostridium difficile pathogenesis.Environmental microbiology · 2018Article
- Ethanolamine Utilization in Bacteria.mBio · 2018Review
- Ethanolamine and Phosphatidylethanolamine: Partners in Health and Disease.Oxidative medicine and cellular longevity · 2017Review
- Comparative transcriptome analysis by RNAseq of necrotic enteritis Clostridium perfringens during in vivo colonization and in vitro conditions.BMC microbiology · 2016Article
- Ethanolamine Signaling Promotes Salmonella Niche Recognition and Adaptation during Infection.PLoS pathogens · 2015Article
- Modulation of the enterohemorrhagic E. coli virulence program through the human gastrointestinal tract.Virulence · 2013Review
- Article
Corrections and comments
- Comment on
Authors and funding
1 author at 1 institution in 1 country.
Funding
Abstract
Ethanolamine (EA) is a compound prevalent in the gastrointestinal (GI) environment. The ability to catabolize this compound has been associated with important GI pathogens, including enterohemorrhagic Escherichia coli O157:H7 (EHEC). It has been hypothesized that the ability of EHEC to utilize EA as a source of nitrogen provides EHEC with an important competitive advantage in the gut. However, new work by Kendall et al. (mBio 3:e00050-12, 2012) suggests that the role of EA in EHEC pathogenesis may be more fundamental; EA appears to be a signal for EHEC to commence its virulence program. In this commentary, I review the previously described connections of EA to bacterial pathogenesis in the GI tract, highlight the important findings of this new study, and note areas where further research is needed to fully comprehend the connection of EA utilization to bacterial pathogenesis.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.