ArticleClinics (Sao Paulo, Brazil)2012
Prognostic value of the six-minute walk test in end-stage renal disease life expectancy: a prospective cohort study.
Article in Clinics (Sao Paulo, Brazil), 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT04898608 (The Effect of Intradialytic Exercise on Dialysis Patients' Survival), which is not on this map. Cited by 36 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
The Effect of Intradialytic Exercise on Dialysis Patients' Survival: A Randomized Controlled Trial
Who cites it
36 citing papers in PubMed, 1 synthesis or guideline pooled it, 79 citations in OpenAlex.
- Minimal clinically important difference for the 6-min walk test: literature review and application to Morquio A syndrome.Orphanet journal of rare diseases · 2017Pooled it
- Effects of intradialytic resistance versus flexibility exercises on clinical outcomes in hemodialysis patients: a pilot randomized controlled trial.BMC nephrology · 2026Trial
- Effect of exercise-based rehabilitation on functional capacity and renal function in type 2 diabetes mellitus with nephropathy: a randomized controlled trial.International urology and nephrology · 2024Trial
- The effect of intradialytic exercise on dialysis patient survival: a randomized controlled trial.BMC nephrology · 2023Trial
- Photobiomodulation therapy increases functional capacity of patients with chronic kidney failure: randomized controlled trial.Lasers in medical science · 2021Trial
- "As du Coeur" study: a randomized controlled trial on quality of life impact and cost effectiveness of a physical activity program in patients with cardiovascular disease.BMC cardiovascular disorders · 2018Trial
- Determining Physical Function Measures for Estimating VOKidney medicine · 2026Article
- Protocol for a Prospective, Multicenter Cohort Study on the Treatment of Chronic Cardiorenal Syndrome with Qishen Yiqi Dropping Pills.Clinical pharmacology : advances and applications · 2026Article
- Article
- Randomized Controlled Trial of Walking Training with and without Blood Flow Restriction in Patients Treated with Maintenance Hemodialysis.Clinical journal of the American Society of Nephrology : CJASN · 2025Article
- Article
- Modifiable Physical Factors That Influence Physical Function for People Receiving Peritoneal Dialysis.Kidney international reports · 2024Article
- Measurement properties of performance-based measures to assess physical function in chronic kidney disease: recommendations from a COSMIN systematic review.Clinical kidney journal · 2023Article
- Exercise intolerance and malnutrition associated with all-cause mortality in elderly patients undergoing peritoneal dialysis: a single-center prospective cohort study.International urology and nephrology · 2023Article
- The Effects of Intradialytic Exercise on Key Indices of Sarcopenia in Patients With End-stage Renal Disease: A Systematic Review of Randomized Controlled Trials.Archives of rehabilitation research and clinical translation · 2023Review
- Effects of a Combined Intradialytic Exercise Training Program on Functional Capacity and Body Composition in Kidney Transplant Candidates.Journal of functional morphology and kinesiology · 2023Article
- Effect of Acupuncture on Functional Capacity in Patients Undergoing Hemodialysis: A Patient-Assessor Blinded Randomized Controlled Trial.Healthcare (Basel, Switzerland) · 2022Article
- Effects of an additional resistance training intervention in hemodialysis patients performing long-term ergometer exercise during dialysis.Journal of physical therapy science · 2022Article
- The Feasibility and User-Experience of a Digital Health Intervention Designed to Prevent Weight Gain in New Kidney Transplant Recipients-The ExeRTiOn2 Trial.Frontiers in nutrition · 2022Article
- Effect of Intradialytic Supine Ergometer Exercise on Hemodialysis Patients with Different Nutritional Status.Physical therapy research · 2022Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
9 authors at 4 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectivesThe six-minute walk test has been widely used to evaluate functional capacity and predict mortality in several populations. Thus, the aim of this study was to evaluate the prognostic value of the six-minute walk test for the life expectancy of end-stage renal disease patients.
methodsPatients over 18 years old who underwent hemodialysis for at least six months were included. Patients with hemodynamic instability, smoking, chronic obstructive pulmonary disease, physical incapacity and acute myocardial stroke in the preceding three months were excluded.
resultsFifty-two patients (54% males; 36+11 years old) were followed for 144 months. The distance walked in the six-minute walk test was a survival predictor for end-stage renal disease patients. In the multivariate analysis, for each 100 meters walked with a 100-meter increment, the hazard ratio was 0.53, with a 95% confidence interval of 0.37-0.74. There was a positive correlation between the distance walked in the six-minute walk test and peak oxygen consumption (r = 0.508). In the multivariate analysis, each year of dialysis treatment represented a 10% increase in death probability; in the severity index analysis, each point on the scale represented an 11% increase in the death risk.
conclusionsWe observed that survival increased approximately 5% for every 100 meters walked in the six-minute walk test, demonstrating that the test is a viable option for evaluating the functional capacity in patients with end-stage renal disease.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.