GuidelineSchmerz (Berlin, Germany)2012
[Etiology and pathophysiology of fibromyalgia syndrome].
Guideline in Schmerz (Berlin, Germany), 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06138171 (Psychological Layers of Nociplastic Pain), which is not on this map. Cited by 26 papers, 8 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Psychological Layers of Nociplastic Pain: Cluster Analysis of The Role of Personality Traits, Defence Mechanisms, Central Sensitization, and Childhood Traumatic Experiences in Patients With Chronic Migraine, Fibromyalgia, and Vulvodynia
Who cites it
26 citing papers in PubMed, 8 syntheses or guidelines pooled it, 72 citations in OpenAlex.
- [Etiology and pathophysiology of fibromyalgia syndrome : Updated guidelines 2017, overview of systematic review articles and overview of studies on small fiber neuropathy in FMS subgroups].Schmerz (Berlin, Germany) · 2017Pooled it
- Oral nonsteroidal anti-inflammatory drugs for fibromyalgia in adults.The Cochrane database of systematic reviews · 2017Pooled it
- Gabapentin for fibromyalgia pain in adults.The Cochrane database of systematic reviews · 2017Pooled it
- Cannabinoids for fibromyalgia.The Cochrane database of systematic reviews · 2016Pooled it
- Antipsychotics for fibromyalgia in adults.The Cochrane database of systematic reviews · 2016Pooled it
- Selective serotonin reuptake inhibitors for fibromyalgia syndrome.The Cochrane database of systematic reviews · 2015Pooled it
- Cognitive behavioural therapies for fibromyalgia.The Cochrane database of systematic reviews · 2013Pooled it
- [Fibromyalgia syndrome. Definition, classification, clinical diagnosis and prognosis].Schmerz (Berlin, Germany) · 2012Guideline
- [Treatment of fibromyalgia syndrome with gamma-hydroxybutyrate : A randomized controlled study].Schmerz (Berlin, Germany) · 2017Trial
- [Fibromyalgia syndrome].Innere Medizin (Heidelberg, Germany) · 2026Review
- Impact of Post-Traumatic Stress Disorder Management Through Reconsolidation Therapy on Fibromyalgia Syndrome: A Pilot Study.Biomedicines · 2026Article
- Fibromyalgia-associated hyperalgesia is related to psychopathological alterations but not to gut microbiome changes.PloS one · 2022Article
- [Pain is modality-specific : Differences in the perception and processing of interoceptive visceral compared to exteroceptive cutaneous heat pain stimuli].Schmerz (Berlin, Germany) · 2018Review
- Severe forms of fibromyalgia with acute exacerbation of pain: costs, comorbidities, and length of stay in inpatient care.ClinicoEconomics and outcomes research : CEOR · 2017Article
- Pregabalin for pain in fibromyalgia in adults.The Cochrane database of systematic reviews · 2016Review
- Oxycodone for pain in fibromyalgia in adults.The Cochrane database of systematic reviews · 2016Review
- [Psychotherapeutic procedures for fibromyalgia syndrome].Zeitschrift fur Rheumatologie · 2015Review
- [Fibromyalgia syndrome: A disease of the small nerve fibers?].Zeitschrift fur Rheumatologie · 2015Review
- Exploring Genetic Susceptibility to Fibromyalgia.Chonnam medical journal · 2015Review
- An insight into the gastrointestinal component of fibromyalgia: clinical manifestations and potential underlying mechanisms.Rheumatology international · 2015Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
14 authors at 12 institutions in 4 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundThe scheduled update to the German S3 guidelines on fibromyalgia syndrome (FMS) by the Association of the Scientific Medical Societies ("Arbeitsgemeinschaft der Wissenschaftlichen Medizinischen Fachgesellschaften", AWMF; registration number 041/004) was planned starting in March 2011. MATERIALS AND
methodsThe development of the guidelines was coordinated by the German Interdisciplinary Association for Pain Therapy ("Deutsche Interdisziplinären Vereinigung für Schmerztherapie", DIVS), 9 scientific medical societies and 2 patient self-help organizations. Eight working groups with a total of 50 members were evenly balanced in terms of gender, medical field, potential conflicts of interest and hierarchical position in the medical and scientific fields. Literature searches were performed using the Medline, PsycInfo, Scopus and Cochrane Library databases (until December 2010). The grading of the strength of the evidence followed the scheme of the Oxford Centre for Evidence-Based Medicine.
resultsCurrent data do not identify distinct etiologic or pathophysiological factors mediating development of FMS. The development of FMS is associated with inflammatory rheumatic diseases (EL2b), with gene polymorphisms of the 5-hydroxytryptamine (HT)(2) receptor (EL3a), lifestyle factors (smoking, obesity, lack of physical activity; EL2b), physical and sexual abuse in childhood and adulthood (EL3a).
conclusionFMS is most likely the result of various pathogenetic factors and pathophysiological mechanisms. The English full-text version of this article is available at SpringerLink (under "Supplemental").
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.