Evidence map›Paper›PMID 22758623›Full record

ReviewCurrent cardiology reviews2011

Cardiotoxicity of molecularly targeted agents.

Nadia Hedhli, Kerry S Russell

Abstract readReview
In one paragraph

Review in Current cardiology reviews, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed.

  1. Observational
  2. Article
  3. Article
  4. Article
  5. Review
  6. Cancer Therapies and Vascular Toxicities.Current treatment options in oncology · 2022
    Review
  7. Artificial intelligence opportunities in cardio-oncology: Overview with spotlight on electrocardiography.American heart journal plus : cardiology research and practice · 2022
    Article
  8. Review
  9. Review
  10. Review
  11. Vascular Complications of Cancer Chemotherapy.The Canadian journal of cardiology · 2016
    Review
  12. Review
  13. Article
  14. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Nadia HedhliDepartment of Internal Medicine-Section of Cardiovascular Medicine, Yale School of Medicine, New Haven, CT 06520-8017, USA.
Kerry S Russell

Funding

Vascular Training GrantT32HL007950 · NHLBI · YALE UNIVERSITY · PI JEFFREY R. BENDER, Daniel Greif · 2000 to 2026
$9.6M
Cardiovascular effects of endothelial-derived neuregulinR01HL080176 · NHLBI · YALE UNIVERSITY · PI RUSSELL, KERRY STRONG · 2006 to 2010
$2.2M
CARDIOVASCULAR SIGNALING EFFECTS OF NEUREGULINSK08HL004429 · NHLBI · YALE UNIVERSITY · PI RUSSELL, KERRY STRONG · 2000 to 2004
$655k
NHLBI NIH HHS K08HL04429NHLBI NIH HHS R01HL80176NHLBI NIH HHS T32HL007950
6 · The paper itself

Abstract

Cardiac toxicity of molecularly targeted cancer agents is increasingly recognized as a significant side effect of chemotherapy. These new potent therapies may not only affect the survival of cancer cells, but have the potential to adversely impact normal cardiac and vascular function. Unraveling the mechanisms by which these therapies affect the heart and vasculature is crucial for improving drug design and finding alternative therapies to protect patients predisposed to cardiovascular disease. In this review, we summarize the classification and side effects of currently approved molecularly targeted chemotherapeutics.

Indexed as

Antineoplastic AgentsCardiotoxinsCardiovascular DiseasesHumansMolecular Targeted TherapyNeoplasmsAntineoplastic AgentsCardiotoxins

Identifiers

PMID22758623
PMCPMC3322440

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.