ArticleJournal of thoracic disease2012
Five-year update on the mouse model of orthotopic lung transplantation: Scientific uses, tricks of the trade, and tips for success.
Article in Journal of thoracic disease, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers, 2 of them syntheses that pooled it.
What it found
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Who cites it
22 citing papers in PubMed, 2 syntheses or guidelines pooled it.
- Pooled it
- Prognostic value of the neutrophil to lymphocyte ratio in lung cancer: A meta-analysis.Clinics (Sao Paulo, Brazil) · 2015Pooled it
- Nanoparticle targeting of neutrophil glycolysis prevents lung ischemia-reperfusion injury.American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons · 2024Article
- Anterior hilum anastomosis versus posterior hilum anastomosis in a mouse lung transplantation model.JTCVS techniques · 2022Article
- Commentary: Back(ward) to the future-novel technique of inverted left lung-right chest lung transplant in rats.JTCVS open · 2022Article
- A Comprehensive Review on the Surgical Aspect of Lung Transplant Models in Mice and Rats.Cells · 2022Review
- α1-Antitrypsin attenuates acute rejection of orthotopic murine lung allografts.Respiratory research · 2021Article
- A Rat Lung Transplantation Model of Warm Ischemia/Reperfusion Injury: Optimizations to Improve Outcomes.Journal of visualized experiments : JoVE · 2021Article
- Chronic lung allograft pathology lesions in two rat strain combinations.Journal of thoracic disease · 2021Article
- Loading Imatinib inside targeted nanoparticles to prevent Bronchiolitis Obliterans Syndrome.Scientific reports · 2020Article
- A Simplified Continuous Two-stitch Suture for Bronchial Anastomosis of Left Single Lung Transplant in Dogs.Current medical science · 2020Article
- Donor pretreatment with nebulized complement C3a receptor antagonist mitigates brain-death induced immunological injury post-lung transplant.American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons · 2018Article
- Pig lung transplant survival model.Nature protocols · 2018Article
- Prognostic nutritional index as a predictor of survival in patients with recurrent cervical cancer.Molecular and clinical oncology · 2018Article
- LTB4 and montelukast in transplantation-related bronchiolitis obliterans in rats.Journal of cardiothoracic surgery · 2017Article
- Prognostic Value of the Neutrophil to Lymphocyte Ratio (NLR) in Lung Cancer CasesAsian Pacific journal of cancer prevention : APJCP · 2017Article
- Mesenchymal stem cells attenuate ischemia-reperfusion injury after prolonged cold ischemia in a mouse model of lung transplantation: a preliminary study.Surgery today · 2017Article
- Mechanisms of graft rejection after lung transplantation.Current opinion in organ transplantation · 2017Review
- Pretreatment prognostic nutritional index is a significant predictor of prognosis in patients with cervical cancer treated with concurrent chemoradiotherapy.Molecular and clinical oncology · 2016Article
- Neutrophil to lymphocyte ratio in the pre-treatment phase of final-line chemotherapy predicts the outcome of patients with recurrent ovarian cancer.Oncology letters · 2016Article
Corrections and comments
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Authors and funding
10 authors.
Funding
Abstract
It has been 5 years since our team reported the first successful model of orthotopic single lung transplantation in the mouse. There has been great demand for this technique due to the obvious experimental advantages the mouse offers over other large and small animal models of lung transplantation. These include the availability of mouse-specific reagents as well as knockout and transgenic technology. Our laboratory has utilized this mouse model to study both immunological and non-immunological mechanisms of lung transplant physiology while others have focused on models of chronic rejection. It is surprising that despite our initial publication in 2007 only few other laboratories have published data using this model. This is likely due to the technical complexity of the surgical technique and perioperative complications, which can limit recipient survival. As two of the authors (XL and WL) have a combined experience of over 2500 left and right single lung transplants, this review will summarize their experience and delineate tips and tricks necessary for successful transplantation. We will also describe technical advances made since the original description of the model.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.