Evidence map›Paper›PMID 22754469›Full record

ArticleInternational journal of environmental research and public health2012

Birth defects in Gaza: prevalence, types, familiarity and correlation with environmental factors.

Awny Naim, Hedaya Al Dalies, Mohammed El Balawi, Eman Salem, Kholud Al Meziny, Raneem Al Shawwa, Roberto Minutolo, Paola Manduca

Open access · goldAbstract read
In one paragraph

Article in International journal of environmental research and public health, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
1.5field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 38 citations in OpenAlex.

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  12. Toxic emissions from a military test site in the territory of Sardinia, Italy.International journal of environmental research and public health · 2013
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 4 institutions in 2 countries.

Awny NaimPalestinian Energy Authority, Gaza, Palestine.
Hedaya Al DaliesAl Shifa Hospital, Gaza, Palestine.
Mohammed El BalawiAl Shifa Hospital, Gaza, Palestine.
Eman SalemAl Shifa Hospital, Gaza, Palestine.
Kholud Al MezinyAl Shifa Hospital, Gaza, Palestine.
Raneem Al ShawwaIT consultant, Gaza, Palestine.
Roberto MinutoloNephrology Department, University of Naples, Via Giovanni Paladino, 80138 Napoli, Italy.
Paola ManducaAl Shifa Hospital, Gaza, Palestine.
Dar Al-Shifa Hospital · PSPalestinian Hydrology Group · PSUniversity of Naples Federico II · ITUniversity of Palestine · PS

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

This is the first report of registration at birth, and of incidence of major structural birth defects (BD) obtained in Gaza at Al Shifa Hospital, where 28% of total births in Gaza Strip occur. Doctors registered 4,027 deliveries, with a protocol comprehensive of clinical, demographic, kin and environmental questions. Prevalence of BD is 14/1,000, without association with intermarriage or gender of the child. Prevalence of late miscarriages and still births are respectively 23.3/1,000 and 7.4/1,000, and of premature births 19.6/1,000. Couples with a BD child have about 10 times higher frequency of recurrence of a BD in their progeny than those with normal children, but none of their 694 siblings and only 10/1,000 of their 1,423 progeny had BD, similar to the frequency in general population. These data suggest occurrence of novel genetic and epigenetic events in determination of BD. Children with BD were born with higher frequency (p < 0 001) in families where one or both parents were under "white phosphorus" attack, that in the general population. Bombing of the family home and removal of the rubble were also frequently reported by couples with BD occurrence. These data suggests a causative/favoring role of acute exposure of parents to the weapons-associated contaminants, and/or of their chronic exposure from their persistence in the environment on the embryonic development of their children.

Indexed as

BombsCongenital AbnormalitiesEnvironmental ExposureEnvironmental PollutantsFemaleHumansInfant, NewbornMaleMiddle EastPregnancyPregnancy ComplicationsPrevalenceEnvironmental Pollutantsenvironmental teratogensexposure to war related eventsfamiliarity of birth defectsmajor structural birth defectsregistration at birth

Identifiers

PMID22754469
PMCPMC3386584
OpenAlexW2051056432

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.