Evidence map›Paper›PMID 22754311›Full record

ArticleInternational journal of molecular sciences2012

Evaluation of antioxidant and antiproliferative properties of three Actinidia (Actinidia kolomikta, Actinidia arguta, Actinidia chinensis) extracts in vitro.

Li-Li Zuo, Zhen-Yu Wang, Zi-Luan Fan, Shuang-Qi Tian, Jia-Ren Liu

Open access · goldAbstract read
In one paragraph

Article in International journal of molecular sciences, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 35 papers.

0numbers the graph read from it
0cells of the map it votes in
35citing papers in PubMed
2.7field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

35 citing papers in PubMed, 137 citations in OpenAlex.

  1. Article
  2. Article
  3. Phenolic Compounds in Berries of Winter-ResistantAntioxidants (Basel, Switzerland) · 2024
    Article
  4. Molecules (Basel, Switzerland) · 2023
    Review
  5. Article
  6. Article
  7. Dwarf Kiwi (Molecules (Basel, Switzerland) · 2022
    Article
  8. Nutritional Values of Minikiwi Fruit (Molecules (Basel, Switzerland) · 2022
    Article
  9. Article
  10. Berries and Leaves ofPlants (Basel, Switzerland) · 2022
    Article
  11. Article
  12. Article
  13. Article
  14. Molecules (Basel, Switzerland) · 2021
    Article
  15. Article
  16. Article
  17. Article
  18. Article
  19. Article
  20. Frontiers in pharmacology · 2019
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 2 countries.

Li-Li ZuoSchool of Food Science and Engineering, Harbin Institute of Technology, 73 HuangHe Road, NanGang District, Harbin 150090, China.
Zhen-Yu WangSchool of Food Science and Engineering, Harbin Institute of Technology, 73 HuangHe Road, NanGang District, Harbin 150090, China.
Zi-Luan FanSchool of Food Science and Engineering, Harbin Institute of Technology, 73 HuangHe Road, NanGang District, Harbin 150090, China.
Shuang-Qi TianSchool of Food Science and Engineering, Harbin Institute of Technology, 73 HuangHe Road, NanGang District, Harbin 150090, China.
Jia-Ren LiuHarvard Medical School, 300 Longwood Ave., Boston, MA 02115-5737, USA.
Harbin Institute of Technology · CNHarvard University · USNortheast Forestry University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The total phenolic content, total flavonoid content, vitamin C content, and antioxidant activities of ethanol extracts from different kiwifruit varieties (Actinidia kolomikta, Actinidia arguta, Actinidia chinensis) were determined in this study. Multiple scavenging activity assays including the hydroxyl radical, O(2) (-)·radical, DPPH, and the ABTS(+) radical scavenging activity assays were used to identify the antioxidant activities of Actinidia extracts. The cell viability of HepG2 and HT-29 cells was also examined in this study. The results demonstrated that the Actinidia kolomikta extract had a higher antioxidant activity than the other two Actinidia extracts. There is a positive correlation between antioxidant activity and the polyphenols and vitamin C content in all three extracts (R(2) ≥ 0.712, p < 0.05). The Actinidia arguta extract had the highest inhibitory effect on HepG2 and HT-29 cell growth. These results provide new insight into the health functions of fruit and demonstrate that Actinidia extracts can potentially have health benefits.

Indexed as

ActinidiaAntioxidantsBenzothiazolesBiphenyl CompoundsCell ProliferationFree RadicalsHep G2 CellsHT29 CellsHumansPicratesPlant ExtractsSulfonic Acids1,1-diphenyl-2-picrylhydrazyl2,2'-azino-di-(3-ethylbenzothiazoline)-6-sulfonic acidAntioxidantsBenzothiazolesBiphenyl CompoundsFree RadicalsPicratesPlant ExtractsSulfonic AcidsActinidiaantioxidant activityantiproliferative activityflavonoidstotal phenolic content

Identifiers

PMID22754311
PMCPMC3382775
OpenAlexW2016387704

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.