ArticleSleep2012
"No thanks, coffee keeps me awake": individual caffeine sensitivity depends on ADORA2A genotype.
Article in Sleep, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
17 citing papers in PubMed, 1 synthesis or guideline pooled it.
- The Caffeinated Brain Part 2: The Effect of Caffeine on Sleep-Related Electroencephalography (EEG)-A Systematic and Mechanistic Review.Nutrients · 2026Pooled it
- Dose and timing effects of caffeine on subsequent sleep: a randomized clinical crossover trial.Sleep · 2025Trial
- Caffeine and attentional control: improved and impaired performance in healthy older adults and Parkinson's disease according to task demands.Psychopharmacology · 2022Trial
- Genetic architecture of a Circadian Imbalance Index: genome-wide association, phenome-wide association, and Mendelian randomisation analyses.EBioMedicine · 2026Article
- Habitual coffee intake shapes the gut microbiome and modifies host physiology and cognition.Nature communications · 2026Article
- Genome wide association study of a Circadian Imbalance Index in 312,935 European ancestry UK Biobank participants identifies loci related to diabetes, mood and myocardial infarction.Research square · 2025Article
- Targeting adenosine 2A receptor signaling suppresses vascular calcification by restraining smooth muscle osteogenic differentiation.Pharmacological research · 2025Article
- Blockade of endothelial adenosine receptor 2 A suppresses atherosclerosis in vivo through inhibiting CREB-ALK5-mediated endothelial to mesenchymal transition.Pharmacological research · 2024Article
- Exploring the gut microbiota: lifestyle choices, disease associations, and personal genomics.Frontiers in nutrition · 2023Review
- Review
- Adenosine, caffeine, and sleep-wake regulation: state of the science and perspectives.Journal of sleep research · 2022Review
- The belated US FDA approval of the adenosine APurinergic signalling · 2020Review
- Sleep in the United States Military.Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology · 2020Review
- Caffeine and Primary (Migraine) Headaches-Friend or Foe?Frontiers in neurology · 2019Review
- Dietary behaviour, psychological well-being and mental distress among adolescents in Korea.Child and adolescent psychiatry and mental health · 2017Article
- Caffeine does not entrain the circadian clock but improves daytime alertness in blind patients with non-24-hour rhythms.Sleep medicine · 2015Article
- Sleep quality and sleep patterns in relation to consumption of energy drinks, caffeinated beverages, and other stimulants among Thai college students.Sleep & breathing = Schlaf & Atmung · 2013Article
Corrections and comments
- Comment on
Authors and funding
1 author.
Funding
No grant is acknowledged in the PubMed record.
Abstract
PubMed holds no abstract for this paper.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.