Trial reportPsychosomatic medicine
Randomized controlled trial of mindfulness-based stress reduction delivered to human immunodeficiency virus-positive patients in Iran: effects on CD4⁺ T lymphocyte count and medical and psychological symptoms.
Trial report in Psychosomatic medicine. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT03848858 (The Efficacy of Eye Movement Desensitization and Reprocessing Therapy Versus Treatment-As-Usual in a Pilot Randomized Controlled Trial in Reducing Clinical Symptoms and Biological Markers of HIV in Patients With a Recent Diagnosis of HIV), which is not on this map. Cited by 29 papers, 8 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
The Efficacy of Eye Movement Desensitization and Reprocessing Therapy Versus Treatment-As-Usual in a Pilot Randomized Controlled Trial in Reducing Clinical Symptoms and Biological Markers of HIV in Patients With a Recent Diagnosis of HIV
Who cites it
29 citing papers in PubMed, 8 syntheses or guidelines pooled it, 78 citations in OpenAlex.
- Mental health interventions for persons living with HIV in low- and middle-income countries: a systematic review.Journal of the International AIDS Society · 2021Pooled it
- Mindfulness-Based Interventions for Adults Living with HIV/AIDS: A Systematic Review and Meta-analysis.AIDS and behavior · 2019Pooled it
- The Benefits of Psychosocial Interventions for Mental Health in People Living with HIV: A Systematic Review and Meta-analysis.AIDS and behavior · 2018Pooled it
- Psychological Treatments for the World: Lessons from Low- and Middle-Income Countries.Annual review of clinical psychology · 2017Pooled it
- Psychosocial group interventions to improve psychological well-being in adults living with HIV.The Cochrane database of systematic reviews · 2017Pooled it
- Mindfulness meditation and the immune system: a systematic review of randomized controlled trials.Annals of the New York Academy of Sciences · 2016Pooled it
- Meditation programs for psychological stress and well-being: a systematic review and meta-analysis.JAMA internal medicine · 2014Pooled it
- Pooled it
- A randomized, controlled trial of mindfulness-based stress reduction in HIV infection.Brain, behavior, and immunity · 2018Trial
- Trial
- Phone-delivered mindfulness training to promote medication adherence and reduce sexual risk behavior among persons living with HIV: Design and methods.Contemporary clinical trials · 2017Trial
- A Mixed-Methods Pilot Study of Mindfulness-Based Stress Reduction for HIV-Associated Chronic Pain.Behavioral medicine (Washington, D.C.)Trial
- Comprehensive Review of Chronic Stress Pathways and the Efficacy of Behavioral Stress Reduction Programs (BSRPs) in Managing Diseases.International journal of environmental research and public health · 2024Review
- Yoga, Meditation, Breathing Exercises, and Inflammatory Biomarkers with Possible Implications in COVID-19: A Systematic Review and Meta-Analysis of Randomized Controlled Trials.Evidence-based complementary and alternative medicine : eCAM · 2022Review
- Process and Outcome Evaluation of a Mindfulness-Based Cognitive Therapy Intervention for Cisgender and Transgender African American Women Living with HIV/AIDS.AIDS and behavior · 2021Article
- Attitudes toward a mindfulness-based intervention from African American women living with HIV: A qualitative study.SAGE open medicine · 2021Article
- Enrollment Length, Service Category, and HIV Health Outcomes Among Low-Income HIV-Positive Persons Newly Enrolled in a Housing Program, New York City, 2014-2017.American journal of public health · 2020Article
- Assessing the Acceptability of a Mindfulness-Based Cognitive Therapy Intervention for African-American Women Living with HIV/AIDS.Journal of racial and ethnic health disparities · 2019Article
- Mind-body practices for people living with HIV: a systematic scoping review.BMC complementary and alternative medicine · 2019Article
- Mindfulness Training and Physical Health: Mechanisms and Outcomes.Psychosomatic medicine · 2019Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors at 1 institution in 1 country.
Funding
Abstract
objectiveTo evaluate the immediate and long-term effectiveness of mindfulness-based stress reduction (MBSR) on biological and symptomatological markers of health among human immunodeficiency virus-positive (HIV+) patients in Tehran, Iran.
methodsUsing a randomized controlled trial design, data from 173 HIV+ patients (CD4 count > 250) not yet receiving antiretroviral therapy, who participated in either an 8-week MBSR (n = 87) or a brief education and support condition (n = 86) at the Imam Khomeini Hospital, were analyzed. Assessments included CD4 count, Symptom Checklist-90-Revised (SCL-90R), and Medical Symptom Checklist (MSCL) at baseline, immediate post-treatment, and at the 3-, 6-, 9-, and 12-month follow-up periods.
resultsThe treatment-adherent sample had a mean (standard deviation) age of 35.1 (6.5) years and 69% were male. Linear mixed-model estimates indicated that, in the MBSR condition, the mean CD4 count increased from baseline up to 9 months after treatment and then returned to baseline level at 12 months. Improvements in mean SCL-90R (up to 6 months) and MSCL (up to 12 months) scores were observed for the MBSR condition, whereas education and support condition scores remained the same over time; however, only MSCL improvements significantly differed between groups and these changes lasted up to the final assessment.
conclusionsFindings suggest that among treatment-adherent Iranian HIV+ patients not yet receiving antiretroviral drug treatment, MBSR seems to have the strongest potential to improve self-reported medical symptoms.
trial registrationIranian Registry of Clinical Trials: IRCT201106084076N2.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.